Calcitonin gene-related peptide (CGRP) antagonists are a class of medications that act as
antagonists of the CGRP receptor or ligand. They can be divided into monoclonal antibodies …

Calcitonin gene-related peptide (CGRP) antagonists are a class of medications that act as
antagonists of the CGRP receptor or ligand. They can be divided into monoclonal antibodies …

Introduction The small molecule non-peptide calcitonin gene-related peptide (CGRP)
receptor antagonists named gepants offer a breakthrough novel approach in migraine acute …

Migraine is a debilitating disease whose clinical and social impact is out of debate.
Tolerability issues, interactions, contraindications, and inefficacy of the available …

Chronic migraine (CM) is a profoundly debilitating condition that has detrimental clinical and
social outcomes. Over the past two decades, novel small-molecule calcitonin gene-related …

Introduction Gepants are small molecules targeting the calcitonin gene-related peptide
(CGRP) that have been recently introduced and are under additional clinical development …

Small molecule calcitonin gene-related peptide (CGRP) receptor antagonists are commonly
referred to as gepants. The first generation of gepants provided the first line of evidence of …

Introduction: Migraine is the most common of all neurological disorders. A breakthrough in
migraine treatment emerged in the early nineties with the introduction of 5-HT1B/D receptor …

Migraine is a prevalent and disabling neurological disease. Its preventive treatment for
decades has been rather limited due to the absence of disease-specific therapies with …

Introduction Migraine is a leading cause of years lived with disability and preventive
strategies represent a mainstay to reduce health-related disability and improve quality of life …