Subchronic Exposure to Mixture of Cadmium, Copper, and Nickel Induces Neurobehavioral Deficits and Hippocampal Oxidative Stress of Wistar Rats

M Lamtai, H Benmhammed, S Azirar… - … Trace Element Research, 2024 - Springer
The present study was aimed at evaluating the influence of the subchronic exposure of
cadmium (Cd), copper (Cu), and nickel (Ni) mixtures on affective behaviors, memory …

Chronic copper exposure leads to hippocampus oxidative stress and impaired learning and memory in male and female rats

M Lamtai, O Zghari, S Ouakki, I Marmouzi… - Toxicological …, 2020 - Springer
Environmental and occupational exposures to copper (Cu) play a pivotal role in the etiology
of some neurological diseases and reduced cognitive functions. However, the precise …

Intrahippocampal effects of nickel injection on the affective and cognitive response in wistar rat: potential role of oxidative stress

MY El Brouzi, M Lamtai, O Zghari, S Ouakki… - … Trace Element Research, 2021 - Springer
The present study focused on affective and cognitive behaviors in male Wistar rats, following
direct and unique exposure to nickel chloride (NiCl 2), as well as the possible involvement of …

[HTML][HTML] Effect of chronic administration of cadmium on anxiety-like, depression-like and memory deficits in male and female rats: possible involvement of oxidative …

M Lamtai, J Chaibat, S Ouakki, I Berkiks, EH Rifi… - Journal of Behavioral …, 2018 - scirp.org
The main objective of this work is to study the effect of chronic administration of cadmium
(Cd) on the level of depression-like, anxiety-like, memory state and oxidative stress in male …

Short term cadmium administration dose dependently elicits immediate biochemical, neurochemical and neurobehavioral dysfunction in male rats

S Haider, L Anis, Z Batool, I Sajid, F Naqvi… - Metabolic brain …, 2015 - Springer
Cadmium is a toxic environmental and industrial pollutant. Cadmium toxicity has been
reported to produce biochemical and behavioral dysfunction that may cause adverse effects …

Concomitant Exposure to Lower Doses of Arsenic, Lead, and Manganese Induces Greater Synergistic Neurotoxicity Than Individual Metals in Mice

E Kabir, TT Shila, J Islam, SA Beauty, F Islam… - … Trace Element Research, 2024 - Springer
People in Bangladesh are often exposed to low to high levels of multiple metals due to
contaminated groundwater with various heavy metals such as arsenic (As), lead (Pb), and …

Effect of cadmium administration on the antioxidant system and neuronal death in the hippocampus of rats

S Treviño, G Pulido, E Fuentes, A Handal‐Silva… - Synapse, 2022 - Wiley Online Library
Cadmium (Cd) is a heavy metal classified as a carcinogen whose exposure could affect the
function of the central nervous system. Studies suggest that Cd modifies neuronal …

[HTML][HTML] Effect of chronic administration of nickel on affective and cognitive behavior in male and female rats: possible implication of oxidative stress pathway

M Lamtai, J Chaibat, S Ouakki, O Zghari, A Mesfioui… - Brain sciences, 2018 - mdpi.com
Nickel (Ni) toxicity has been reported to produce biochemical and behavioral dysfunction.
The present study was undertaken to examine whether Ni chronic administration can induce …

Essential Trace Elements Prevent the Impairment in the Retention Memory, Cerebral Cortex, and Cerebellum Damage in Male Rats Exposed to Quaternary Metal …

EU Ikpeama, CN Orish, AN Ezejiofor, J Rovira… - Neuroscience, 2023 - Elsevier
In the present study, we examined adverse effects of metals and metalloids in the Cerebral
cortex (CC) and Cerebellum (CE). Group 1 comprised from the controls while other four …

[HTML][HTML] Nickel and aluminium mixture elicit memory impairment by activation of oxidative stress, COX-2, and diminution of AChE, BDNF and NGF levels in cerebral …

CP Anyachor, CN Orish, AN Ezejiofor, A Cirovic… - Current Research in …, 2023 - Elsevier
This study evaluated nickel and aluminium-induced neurotoxicity, as a binary metal mixture.
Twenty-eight male Sprague Dawley albino rats were weight-matched and divided into four …