Chronic neuropathic pain is one of the primary causes of disability subsequent to spinal cord
injury. Patients experiencing neuropathic pain after spinal cord injury suffer from poor quality …

Background Brachial plexus avulsion (BPA) animally involves the separation of spinal nerve
roots themselves and the correlative spinal cord segment, leading to formidable neuropathic …

As an intractable health threat, neuropathic pain is now a key problem in clinical therapy,
which can be caused by lesions affecting the peripheral nervous systems. 1, 8-cineole is a …

Neuropathic pain is a severe health problem for which there is a lack of effective therapy.
Ozone and Gardenia fruits have been used separately in pain relief for many years; …

ATP facilitates initiation and transmission of the neuropathic pain at the dorsal root ganglion
(DRG) level via the P2X receptors, especially the subtype P2X3. Lappaconitine (LA) is an …

Background Experiments were conducted to evaluate the contribution of P2X4 receptors to
the modulation of neuropathy and their ability to amplify opioid effectiveness. Methods The …

Neuropathic pain is becoming an intractable health threat, with its profound effect on quality
of life, thus posing a major challenge to clinical therapy. Despite the reported efficacy of …

Tissue injury or inflammation of the nervous system may result in chronic neuropathic pain
characterized by sensitivity to painful stimuli. P2X3 receptors play a crucial role in facilitating …

cineole is a natural monoterpene cyclic ether present in eucalyptus and has been reported
to exhibit anti-inflammatory and antioxidant effects. The therapeutic effects of 1, 8-cineole on …

Electroacupuncture has been shown to effectively reduce chronic pain in patients with nerve
injury. The underlying mechanisms are not well understood. Accumulated evidence …