Estrogen receptor (ER) is a ligand-activated transcription factor that mediates estrogen
actions in target tissues. Several common polymorphisms of the ER-α gene have been …

The estrogen receptor-alpha (ERα) has been known to play a role in the development and
progression of breast cancer. Several genetic polymorphisms in the ERα gene have been …

Recent studies suggest that genetic polymorphisms of the estrogen receptor-α (ER-α) gene
may be associated with breast cancer risk. To evaluate the role of this gene in the risk of …

Purpose: The effects of estrogens are mediated primarily through estrogen receptor (ER) in
breast tissue, and polymorphisms in the ER genes may alter the functions of these receptors …

Long-term estrogen exposure and family history of breast cancer are the two factors that are
most consistently found to be associated with breast cancer risk. Sequence variants in …

Introduction Receptor-mediated estrogen activation participates in the development and
progression of breast cancer. Estrogen receptor (ER)-α polymorphism has been found to be …

We conducted a hospital-based case-control study to evaluate the association between the
XbaI and PvuII restriction fragment length polymorphisms (RFLPs) in intron 1 of the estrogen …

Estrogens exert their effect on the breast through the estrogen receptor. We prospectively
investigated breast cancer risk associated with 2 polymorphic sites in the estrogen receptor …

The estrogen signal is mediated by the estrogen receptor (ER). The specific role of ER-beta,
a second ER, in breast carcinogenesis is not known. A number of association studies have …

The estrogen receptor (ER) and the human epithelial growth factor receptor 2 (HER2) genes
have been implicated in the development and prognosis of breast cancer. Several genetic …