Autophagy in the diabetic heart: a potential pharmacotherapeutic target in diabetic cardiomyopathy
S Dewanjee, J Vallamkondu, RS Kalra, A John… - Ageing research …, 2021 - Elsevier
Association of diabetes with an elevated risk of cardiac failure has been clinically evident.
Diabetes potentiates diastolic and systolic cardiac failure following the myocardial infarction …
Diabetes potentiates diastolic and systolic cardiac failure following the myocardial infarction …
The interplay between autophagy and apoptosis in the diabetic heart
C Ouyang, J You, Z Xie - Journal of Molecular and Cellular Cardiology, 2014 - Elsevier
Diabetic cardiomyopathy is characterized by ventricular dysfunction that occurs in diabetic
patients independent of coronary artery disease, hypertension, and any other cardiovascular …
patients independent of coronary artery disease, hypertension, and any other cardiovascular …
[HTML][HTML] Autophagy and mitophagy in diabetic cardiomyopathy
S Kobayashi, Q Liang - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Diabetic cardiomyopathy is a heart muscle-specific disease that increases the risk of heart
failure and mortality in diabetic patients independent of vascular pathology. Mitochondria …
failure and mortality in diabetic patients independent of vascular pathology. Mitochondria …
Cardiovascular autophagy: concepts, controversies, and perspectives
Despite recent scientific and technological advances, cardiovascular disease remains the
leading cause of morbidity and mortality worldwide. Autophagy, an evolutionarily ancient …
leading cause of morbidity and mortality worldwide. Autophagy, an evolutionarily ancient …
Autophagy, metabolic disease, and pathogenesis of heart dysfunction
F Wang, J Jia, B Rodrigues - Canadian Journal of Cardiology, 2017 - Elsevier
In normal physiology, autophagy is recognized as a protective housekeeping mechanism
that enables elimination of unhealthy organelles, protein aggregates, and invading …
that enables elimination of unhealthy organelles, protein aggregates, and invading …
[HTML][HTML] Macroautophagy and chaperone-mediated autophagy in heart failure: the known and the unknown
R Ghosh, JS Pattison - Oxidative Medicine and Cellular Longevity, 2018 - hindawi.com
Cardiac diseases including hypertrophic and ischemic cardiomyopathies are increasingly
being reported to accumulate misfolded proteins and damaged organelles. These findings …
being reported to accumulate misfolded proteins and damaged organelles. These findings …
Therapeutic targeting of autophagy: potential and concerns in treating cardiovascular disease
AM Orogo, ÅB Gustafsson - Circulation research, 2015 - Am Heart Assoc
Autophagy is an evolutionarily conserved process by which long-lived proteins and
organelles are sequestered by autophagosomes and subsequently degraded by lysosomes …
organelles are sequestered by autophagosomes and subsequently degraded by lysosomes …
Myocardial stress and autophagy: mechanisms and potential therapies
LMD Delbridge, KM Mellor, DJ Taylor… - Nature Reviews …, 2017 - nature.com
Autophagy is a ubiquitous cellular catabolic process responsive to energy stress. Research
over the past decade has revealed that cardiomyocyte autophagy is a prominent …
over the past decade has revealed that cardiomyocyte autophagy is a prominent …
Comprehensive autophagy evaluation in cardiac disease models
N Kaludercic, MC Maiuri, S Kaushik… - Cardiovascular …, 2020 - academic.oup.com
Autophagy is a highly conserved recycling mechanism essential for maintaining cellular
homeostasis. The pathophysiological role of autophagy has been explored since its …
homeostasis. The pathophysiological role of autophagy has been explored since its …
Recycle or die: the role of autophagy in cardioprotection
ÅB Gustafsson, RA Gottlieb - Journal of molecular and cellular cardiology, 2008 - Elsevier
Autophagy is a highly conserved cellular process responsible for the degradation of long-
lived proteins and organelles. Autophagy occurs at low levels under normal conditions, but …
lived proteins and organelles. Autophagy occurs at low levels under normal conditions, but …