Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles
Resident macrophages orchestrate homeostatic, inflammatory, and reparative activities. It is
appreciated that different tissues instruct specialized macrophage functions. However …
appreciated that different tissues instruct specialized macrophage functions. However …
Macrophages: development and tissue specialization
C Varol, A Mildner, S Jung - Annual review of immunology, 2015 - annualreviews.org
Macrophages are myeloid immune cells that are strategically positioned throughout the
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …
Tissue-specific macrophages: how they develop and choreograph tissue biology
Macrophages are innate immune cells that form a 3D network in all our tissues, where they
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …
Origin, development, and homeostasis of tissue‐resident macrophages
M Haldar, KM Murphy - Immunological reviews, 2014 - Wiley Online Library
Macrophages are versatile cells of the hematopoietic system that display remarkable
functional diversity encompassing innate immune responses, tissue development, and …
functional diversity encompassing innate immune responses, tissue development, and …
Developmental origin of lung macrophage diversity
SYS Tan, MA Krasnow - Development, 2016 - journals.biologists.com
Macrophages are specialized phagocytic cells, present in all tissues, which engulf and
digest pathogens, infected and dying cells, and debris, and can recruit and regulate other …
digest pathogens, infected and dying cells, and debris, and can recruit and regulate other …
Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues
J Qie, Y Liu, Y Wang, F Zhang, Z Qin, S Tian… - Nature …, 2022 - nature.com
Macrophages are involved in tissue homeostasis and are critical for innate immune
responses, yet distinct macrophage populations in different tissues exhibit diverse gene …
responses, yet distinct macrophage populations in different tissues exhibit diverse gene …
Tissue biology perspective on macrophages
Y Okabe, R Medzhitov - Nature immunology, 2016 - nature.com
Macrophages are essential components of mammalian tissues. Although historically known
mainly for their function in host defense and the clearance of apoptotic cells, macrophages …
mainly for their function in host defense and the clearance of apoptotic cells, macrophages …
[HTML][HTML] Determinants of resident tissue macrophage identity and function
Resident tissue macrophages (RTMs) have a broad spectrum of immune-and non-immune-
related tissue-supporting activities. The roots of this heterogeneity and versatility are only …
related tissue-supporting activities. The roots of this heterogeneity and versatility are only …
A common framework of monocyte-derived macrophage activation
Macrophages populate every organ during homeostasis and disease, displaying features of
tissue imprinting and heterogeneous activation. The disconnected picture of macrophage …
tissue imprinting and heterogeneous activation. The disconnected picture of macrophage …
Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities
Peritoneal macrophages are one of the most studied macrophage populations in the body,
yet the composition, developmental origin and mechanisms governing the maintenance of …
yet the composition, developmental origin and mechanisms governing the maintenance of …