“COAGULATION”: a mnemonic device for treating coagulation disorders following traumatic brain injury—a narrative-based method in the intensive care unit

M Quintana-Diaz, P Anania, R Juárez-Vela… - Frontiers in Public …, 2023 - frontiersin.org
Introduction Coagulopathy associated with isolated traumatic brain injury (C-iTBI) is a
frequent complication associated with poor outcomes, primarily due to its role in the …

Global characterisation of coagulopathy in isolated traumatic brain injury (iTBI): a CENTER-TBI analysis

JK Böhm, H Güting, S Thorn, N Schäfer, V Rambach… - Neurocritical care, 2021 - Springer
Background Trauma-induced coagulopathy in patients with traumatic brain injury (TBI) is
associated with high rates of complications, unfavourable outcomes and mortality. The …

Traumatic brain injury-associated coagulopathy

J Zhang, R Jiang, L Liu, T Watkins, F Zhang… - Journal of …, 2012 - liebertpub.com
Traumatic injury is a common cause of coagulopathy, primarily due to blood loss and
hemodilution secondary to fluid resuscitation. Traumatic injury-associated coagulopathy …

Coagulopathy in isolated traumatic brain injury: myth or reality

R Mathur, JI Suarez - Neurocritical care, 2023 - Springer
Abstract Introduction Traumatic Brain Injury (TBI) has been shown to be associated with
altered hemostasis and coagulopathy, that correlates with worsening secondary injury and …

Acute traumatic coagulopathy in the setting of isolated traumatic brain injury: a systematic review and meta-analysis

DS Epstein, B Mitra, G O'Reilly, JV Rosenfeld… - Injury, 2014 - Elsevier
Background and objectives Acute traumatic coagulopathy (ATC) has been reported in the
setting of isolated traumatic brain injury (iTBI) and associated with high mortality and poor …

Coagulopathy and progression of intracranial hemorrhage in traumatic brain injury: mechanisms, impact, and therapeutic considerations

M Maegele - Neurosurgery, 2021 - journals.lww.com
BACKGROUND Traumatic brain injury (TBI) remains one of the most challenging health and
socioeconomic problems of our times. Clinical courses may be complicated by hemostatic …

Traumatic brain injury provokes low fibrinolytic activity in severely injured patients

JP Meizoso, HB Moore, EE Moore… - Journal of Trauma …, 2022 - journals.lww.com
Background Traumatic brain injury (TBI) in combination with shock has been associated with
hypocoagulability. However, recent data suggest that TBI itself can promote a systemic …

2347 Traumatic brain injury coagulopathy is associated with raised intracranial pressure, 7-day progression of haemorrhage and mortality

C Lindsay, R Davenport, K Brohi - 2023 - emj.bmj.com
Aims and Objectives Traumatic brain injury is suspected of inducing coagulopathy but the
evidence to support this is conflicting. Systemic analyses in isolated TBI (ITBI) have not …

Pathophysiology of coagulopathy induced by traumatic brain injury is identical to that of disseminated intravascular coagulation with hyperfibrinolysis

T Wada, A Shiraishi, S Gando, K Yamakawa… - Frontiers in …, 2021 - frontiersin.org
Background: Traumatic brain injury (TBI)-associated coagulopathy is a widely recognized
risk factor for secondary brain damage and contributes to poor clinical outcomes. Various …

Changes in coagulation following brain injury

M Maegele, J Aversa, MK Marsee… - … in Thrombosis and …, 2020 - thieme-connect.com
Traumatic brain injury (TBI) is a worldwide public health concern due to increasing mortality,
affecting around 10 million patients per year. A wide variety of clinical presentations are a …