In order to maintain shape and withstand intracellular pressure, most bacteria are
surrounded by a cell wall that consists mainly of the cross-linked polymer peptidoglycan …

During growth and propagation, a bacterial cell enlarges and subsequently divides its
peptidoglycan (PG) sacculus, a continuous mesh‐like layer that encases the cell membrane …

Bacterial cell wall synthesis is the target for some of our most powerful antibiotics and has
thus been the subject of intense research focus for more than 50 years. Surprisingly, we still …

Multi-protein complexes organized by cytoskeletal proteins are essential for cell wall
biogenesis in most bacteria. Current models of the wall assembly mechanism assume that …

Peptidoglycan (PG) is an essential structural component of the bacterial cell wall and
maintains the integrity and shape of the cell by forming a continuous layer around the …

Walls of gram‐positive bacteria are dynamically variable and flexible structures that enclose
and protect the underlying cytoplasmic membranes. The wall serves to protect the …

Bacterial cells are fortified against osmotic lysis by a cell wall made of peptidoglycan (PG).
Synthases called penicillin‐binding proteins (PBPs), the targets of penicillin and related …

The Gram-negative bacterial cell envelope is a complex multilayered structure comprising a
bilayered phospholipid (PL) membrane that surrounds the cytoplasm (inner membrane or …

The bacterial cell wall is a complex three-dimensional structure that protects the cell from
environmental stress and ensures its shape. The biosynthesis of its main component, the …

The peptidoglycan (PG) cell wall is a unique macromolecule responsible for both shape
determination and cellular integrity under osmotic stress in virtually all bacteria. A …