Cystic fibrosis (CF) is the most common life-threatening monogenic disease afflicting
Caucasian people. It affects the respiratory, gastrointestinal, glandular and reproductive …

Cystic fibrosis (CF) is a lethal inherited disease caused by mutations in the CF
transmembrane conductance regulator (CFTR) gene, which result in impairment of CFTR …

Introduction Cystic fibrosis (CF) is a life-threatening inherited disease caused by mutations
in the gene encoding the CF transmembrane conductance regulator (CFTR) protein, an …

With the discovery of the CFTR gene in 1989, the search for therapies to improve the basic
defects of cystic fibrosis (CF) commenced. Pharmacological manipulation provides the …

Cystic fibrosis (CF) is the most common life-shortening genetic disease affecting~ 1 in 3,500
of the Caucasian population. CF is caused by mutations in the CF transmembrane …

Mutations of the CFTR gene cause cystic fibrosis (CF), the most common recessive
monogenic disease worldwide. These mutations alter the synthesis, processing, function, or …

Cystic fibrosis (CF) is the most frequent life-limiting autosomal recessive disorder in the
Caucasian population. It is due to mutations in the Cystic Fibrosis Transmembrane …

Cystic fibrosis is a severe autosomal recessive disorder caused by mutations in the cystic
fibrosis transmembrane conductance regulator (CFTR) gene encoding the CFTR protein, a …

Cystic fibrosis (CF) is the most common life-limiting inherited disease in Caucasian
populations, affecting approximately 80,000 people worldwide. CF is a complex multi-organ …

Cystic fibrosis (CF) is an autosomal recessive genetic disease characterized by mutations in
the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is a chloride …