Objectives Ambient temperature impinges on energy metabolism in a body size dependent
manner. This has implications for the housing temperature at which mice are best compared …

In 2012, Speakman and Keijer published a paper in which they arrived at the conclusion that
to obtain metabolic rates of 1.7 times BMR in mice, the mice should be kept at about 23 C [2] …

Objectives The laboratory mouse is presently the most common model for examining
mechanisms of human physiology and disease. Housing temperatures can have a large …

Mice as experimental models for human physiology: when several degrees in housing
temperature matter | Nature Metabolism Skip to main content Thank you for visiting nature.com …

Objectives We quantified the effect of environmental temperature on mouse energy
homeostasis and body temperature. Methods The effect of environmental temperature (4 …

Objective To improve understanding of mouse energy homeostasis and its applicability to
humans, we quantitated the effects of housing density on mouse thermal physiology in both …

It has been argued that mice should be housed at 30° C to best mimic the thermal conditions
experienced by humans, and that the current practice of housing mice at 20–22° C impairs …

The relationships between metabolic rate, body temperature (Tb), body composition and
ageing are complex, and not fully resolved. In particular, Tb and metabolic rate often change …

Basal metabolic rate (BMR) is often assumed to be indicative of the energy turnover at
ambient temperatures (T a) below the thermoneutral zone (SMR), but this assumption has …

Mice are widely used for exploring obesity physiology and treatment. However, thermal
biology is different between small and large mammals. In this Review, we discuss how the …