Scope Energy deprivation in the myocardium is associated with impaired heart function. This
study aims to investigate if aspalathin (ASP) can ameliorate hyperglycemic‐induced shift in …

Aspalathin, a C-glucosyl dihydrochalcone, has previously been shown to protect
cardiomyocytes against hyperglycemia-induced shifts in substrate preference and …

Chronic hyperglycemia is closely associated with impaired substrate metabolism,
dysregulated mitochondrial membrane potential, and apoptosis in the diabetic heart. As …

Aspalathin (ASP) can protect H9c2 cardiomyocytes against high glucose (HG)-induced shifts
in myocardial substrate preference, oxidative stress, and apoptosis. The protective …

H9c2 cardiomyoblast cell line was used to examine the protection of three triterpenes,
asiatic acid, boswellic acid, and oleanolic acid, at 5 or 10 μM against high-glucose-induced …

Background Diabetic cardiomyopathy is characterized by both systolic and diastolic
dysfunction due to decreased contractility, as well as reduced compliance of the …

Objectives The aim of this study is to investigate antidiabetic effects and molecular
mechanisms of the chemical Chikusetsu saponin IVa (CHS) that isolated from root bark of A …

Rooibos, an indigenous South African plant ingested as herbal tea, is well known for its
antioxidant effects. This in vitro study investigated aspalathin (C 21 H 24 O 11), a …

High glucose and high fat are important inducements for the development and progression
of diabetic cardiopathy. Salvianolic acid B (SAB), which is the most abundant and bioactive …

Background Diabetic cardiomyopathy (DCM) is linked to disturbance in cardiac glucose
handling and increased cardiac glycogen storage. This study tested the potential role of …