The three most important recognized risks for prostate cancer (PCa) are increasing age,
ancestry, and family history of the disease. The clustering of PCa within families can be …

Prostate cancer (PCa) is the most common solid organ malignancy diagnosed in American
men and the second leading cause of cancer-related mortality. In the United States, 192,000 …

Objective Prostate cancer is the second most frequent cancer in men worldwide and kills
over 250,000 men worldwide every year. Prostate cancer is a heterogeneous disease at the …

Prostate cancer (PCa) is the most common cancer among men with a lifetime risk of 12%
and median age of diagnosis of 66. 1 In 2020, 191,930 new cases are expected to be …

Current epidemiologic and genetic data suggest the hypothetical paradigm that prostate
cancer occurs in three forms: sporadic, familial, and hereditary (Figure 1). Sporadic cases …

Prostate cancer (PC) is the most frequent malignant tumor among men over 50 years old. Its
incidence varies according to countries and ethnic groups. Known risk factors are race and …

A genetic component in prostate cancer has been recognized for decades. Through
numerous epidemiological and molecular biological studies much evidence has …

Goh CL, Schumacher FR, Easton D, Muir K, Henderson B, Kote‐Jarai Z, Eeles RA (The
Institute of Cancer Research, Sutton, Surrey, UK; Keck School of Medicine, University of …

In 2006 alone, nearly 234,460 men in the USA will be diagnosed with prostate cancer (PC).
In addition, about 27,000 will die from, rather than with, their disease (1). Although there is …

Positive family history of prostate cancer (PCa) has been consistently associated with
increased PCa risk [1]. It is widely used in clinical practice and is a strong indication …