[HTML][HTML] Daytime and outcomes after cardiac surgery: systematic review and metaanalysis, insights from a large UK database review and post-hoc trial analysis

DP Fudulu, A Dimagli, L Dixon, M Sandhu… - The Lancet Regional …, 2021 - thelancet.com
Background Several studies have suggested a variation of myocardial tolerance to
ischaemia depending on the daytime of surgery. To test this hypothesis, we conducted a …

Weekday and survival after cardiac surgery—a Swedish Nationwide cohort study in 106 473 patients

M Dalén, G Edgren, T Ivert, MJ Holzmann… - Journal of the …, 2017 - Am Heart Assoc
Background The purpose of this study was to investigate the association between weekday
of surgery and survival following cardiac surgery. Methods and Results In a nationwide …

Daytime-dependent cardioprotection in cardiac surgery: a large propensity-matched cohort study

PS Kenney, PH Nielsen, IS Modrau - The Annals of Thoracic Surgery, 2020 - Elsevier
Background A recent article provided compelling evidence for a cardioprotective effect of
afternoon compared with morning operation in patients undergoing aortic valve …

Weekday and outcomes of elective cardiac surgery in the UK: a large retrospective database analysis

DP Fudulu, A Dimagli, S Sinha… - European Journal of …, 2022 - academic.oup.com
OBJECTIVES Several studies have shown worse outcomes in patients operated on later in
the week. We tested this hypothesis in a large UK national audit database in elective …

Does the “weekend effect” for postoperative mortality stand up to scrutiny? Association for cardiothoracic anesthesia and critical care cohort study of 110,728 cardiac …

O Papachristofi, AA Klein, J Mackay, S Nashef… - Journal of cardiothoracic …, 2018 - Elsevier
Objective Ongoing debate focuses on whether patients admitted to the hospital on
weekends have higher mortality than those admitted on weekdays. Whether this apparent …

Cardiac surgery in the afternoon is not associated with increased operative morbidity and mortality

V Bianco, E Aranda‐Michel… - Journal of Cardiac …, 2021 - Wiley Online Library
Background Time of day for surgical procedures has been a topic of considerable
controversy, with some suggesting that later operating times are associated with worse …

Daytime variation in aortic valve surgery and clinical outcome: a propensity score–matched analysis

J Götte, A Zittermann, MA Deutsch, R Schramm… - The Annals of Thoracic …, 2020 - Elsevier
Background Time of day potentially impacts outcomes in cardiac surgery. Therefore, the
goal of this study was to assess whether elective aortic valve replacement surgery …

[HTML][HTML] Daytime variation does not impact outcome of cardiac surgery: results from a diverse, multi-institutional cardiac surgery network

S Nemeth, S Schnell, M Argenziano, Y Ning… - The Journal of Thoracic …, 2021 - Elsevier
Objective Recent single-center and experimental data suggested greater adverse cardiac
events for patients undergoing aortic valve replacement (AVR) in the morning (AM) versus …

Daytime variation of clinical outcome in cardiac surgery: A propensity-matched cohort study

M Michaud, V Béland, N Noiseux, J Forcillo… - … of Cardiothoracic and …, 2021 - Elsevier
Objective The purpose of the present study was to investigate the hypothesis of a
nychthemeral variation in the tolerance to ischemia and reperfusion injury in adult cardiac …

[HTML][HTML] Circadian rhythms influence surgical outcomes

GB Lim - Nature Reviews Cardiology, 2018 - nature.com
The outcomes of cardiac surgery could be better if the procedure is performed in the
afternoon rather than in the morning. This effect seems to be transcriptionally controlled by …