In vertebrates, a nuclear cap-binding complex (CBC) formed by two cap-binding proteins,
CBP20 and CBP80, is involved in several steps of RNA metabolism, including pre-mRNA …

The heterodimeric nuclear cap binding complex (CBC) binds to 5′-capped polymerase II
transcripts. It enhances the efficiency of several mRNA maturation steps and is essential for …

Abstract hnRNP F was identified in a screen for proteins that interact with human CBP80 and
CBP20, the components of the nuclear cap-binding complex (CBC). In vitro interaction …

It has previously been shown that efficient export of U1 snRNA or of microinjected, in vitro
synthesized, RNA transcripts from the nucleus of Xenopus oocytes is facilitated by their …

The heterodimeric nuclear cap-binding complex (CBC) binds to the mono-methylated 5′
cap of eukaryotic RNA polymerase II transcripts such as mRNA and U snRNA. The binding …

It has been shown that the monomethylated cap structure plays important roles in nuclear
events. The cap structure has been implicated in the enhancement of pre-mRNA splicing …

Communication between the 5′ and 3′ ends is a common feature of several aspects of
eukaryotic mRNA metabolism. In the nucleus, the pre-mRNA 5′ end is bound by the …

Several observations made over the past year have forged strong molecular links between
transcription by RNA polymerase II (Pol II) and pre-mRNA processing. The key findings …

A number of RNA-binding proteins are associated with mRNAs in both the nucleus and the
cytoplasm. One of these, Npl3p, is a heterogeneous nuclear ribonucleoprotein-like protein …

CAP structures are added cotranscriptionally to all RNA polymer-ase II transcripts1, 2. They
affect several processes including RNA stability3–5, pre-messenger RNA splicing6–11 …