In this paper, as an active ingredient, puerarin chitosan nanoparticles (Pur-CS/TPP-NPs) are
prepared by an ionic gelation method. The chitosan (CS) concentration, pH of the CS …

The interest using novel drug delivery systems to improve oral bioavailability of drug with
poor solubility is increasing. In this study, a new oral delivery system, polybutylcyanoacrylate …

To improve the water solubility and dissolution rate, puerarin (PUE) was nanocrystallized by
an emulsion solvent evaporation (ESE) method, followed by freeze-drying. The optimized …

Berberine chloride (BER) is a benzylisoquinoline alkaloid known for its antihypertensive,
antihyperglycemic, antitumor, anti-inflammatory and antioxidant activities. BER has limited …

A rationally designed oral delivery carrier must overcome various significant barriers in the
gastrointestinal (GI) tract prior to delivery to the bloodstream. One of these barriers is the low …

Objective: The objective of the present investigation was to fabricate and characterize
allopurinol loaded chitosan nanoparticles (A-CNPs) for sustained release of drug. Methods …

Puerarin, which is extracted from traditional Chinese medicine, is widely used in clinic in
China and mainly used as a therapeutic agent to cardiovascular diseases. Owing to its poor …

Nanoparticles have gained considerable attention in recent years as one of the most
promising drug delivery systems owing to their unique potentials via combining the different …

Natural polymers are reliable compounds in drug delivery systems (DDS). Herein, two series
of safe and reliable polyelectrolyte hydrogels (PEHs) were prepared from two oppositely …

Recently, multifunctional drug delivery systems (DDSs) have been designed to provide a
comprehensive approach with multiple functionalities, including diagnostic imaging …