Clinicopathological significance of the single nucleotide polymorphism, rs2853669 within the TERT promoter in papillary thyroid carcinoma

T Hirokawa, Y Arimasu, T Chiba… - Pathology …, 2020 - Wiley Online Library
Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy. Point mutations
in the telomerase reverse transcriptase (TERT) promoter, C228T and C250T and oncogene …

TERT genetic polymorphism rs2736100 is associated with an aggressive manifestation of papillary thyroid carcinoma

X Nie, J Shang, W Wang - Frontiers in Surgery, 2023 - frontiersin.org
Objectives TERT rs2736100 genetic polymorphism is commonly found in human
malignancies, indicating its key role in cancer cell transformation. The aim of this study is to …

TERT promoter and BRAF V600E mutations in papillary thyroid cancer: a single-institution experience in Korea

MJ Kim, JK Kim, GJ Kim, SW Kang, J Lee, JJ Jeong… - Cancers, 2022 - mdpi.com
Simple Summary TERT promoter mutation has recently emerged as a promising prognostic
biomarker for aggressive papillary thyroid cancer (PTC), along with BRAF B600E mutation …

Prognostic Significance of TERT Promoter Mutations in Papillary Thyroid Carcinomas in a BRAFV600E Mutation–Prevalent Population

SE Lee, TS Hwang, YL Choi, HS Han, WS Kim… - Thyroid, 2016 - liebertpub.com
Background: The role of telomerase reverse transcriptase (TERT) promoter mutations in
differentiated thyroid cancer has been well established. These mutations have a significantly …

[HTML][HTML] BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients

L Jin, E Chen, S Dong, Y Cai, X Zhang, Y Zhou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The role of telomerase reverse transcriptase (TERT) gene promoter mutations in the
aggressiveness of papillary thyroid cancer (PTC) remains to be further investigated. Here we …

BRAF V600E and TERT promoter mutations in papillary thyroid carcinoma in Chinese patients

J Sun, J Zhang, J Lu, J Gao, X Ren, L Teng, H Duan… - PLoS …, 2016 - journals.plos.org
Background The BRAF V600E and telomerase reverse transcriptase (TERT) promoter
mutations have been reported in papillary thyroid carcinoma (PTC). The aim of this …

Distinct transcriptional and prognostic impacts of TERT promoter mutations C228T and C250T in papillary thyroid carcinoma

VR Marczyk, AL Maia… - Endocrine-Related …, 2024 - erc.bioscientifica.com
TERT promoter mutations C228T and C250T are associated with disease aggressiveness
and poor clinical outcomes in patients with papillary thyroid carcinomas. However, very little …

TERT promoter mutations and Ki-67 labeling index as a prognostic marker of papillary thyroid carcinomas: combination of two independent factors

M Matsuse, T Yabuta, V Saenko, M Hirokawa… - Scientific reports, 2017 - nature.com
Although most papillary thyroid carcinomas (PTCs) have a good prognosis, a small but
certain fraction shows aggressive behavior. Therefore, a novel and well-performing …

[HTML][HTML] Highly prevalent BRAF V600E and low-frequency TERT promoter mutations underlie papillary thyroid carcinoma in Koreans

SY Kim, T Kim, K Kim, JS Bae… - Journal of Pathology …, 2020 - synapse.koreamed.org
Background The presence of telomerase reverse transcriptase (TERT) promoter mutations
have been associated with a poor prognosis in patients with papillary thyroid carcinomas …

Mutations of the TERT promoter are associated with aggressiveness and recurrence/distant metastasis of papillary thyroid carcinoma

R Liu, Y Li, W Chen, J Cong, Z Zhang… - Oncology …, 2020 - spandidos-publications.com
Several previous studies have shown that mutations in B‑Raf proto‑oncogene (BRAF) and
telomerase reverse transcriptase (TERT) can be used for the diagnosis and prognosis of …