Bone marrow mesenchymal stem cell exosomes suppress phosphate-induced aortic calcification via SIRT6–HMGB1 deacetylation
W Wei, X Guo, L Gu, J Jia, M Yang, W Yuan… - Stem cell research & …, 2021 - Springer
Background Vascular calcification associated with chronic kidney disease (CKD) can
increase the risk of mortality. Elevated serum levels of high mobility group box 1 (HMGB1) …
increase the risk of mortality. Elevated serum levels of high mobility group box 1 (HMGB1) …
Bone marrow mesenchymal stem cell–derived exosomes alleviate high phosphorus-induced vascular smooth muscle cells calcification by modifying microRNA …
Y Guo, S Bao, W Guo, Z Diao, L Wang, X Han… - Functional & integrative …, 2019 - Springer
Vascular calcification is a common complication in patients with chronic kidney disease
(CKD). It is an important predictor of cardiovascular disease and all-cause mortality …
(CKD). It is an important predictor of cardiovascular disease and all-cause mortality …
[HTML][HTML] Exosomes derived from bone marrow mesenchymal stem cells inhibit human aortic vascular smooth muscle cells calcification via the miR-15a/15b/16/NFATc3 …
F Luo, W Guo, W Liu - Biochemical and Biophysical Research …, 2022 - Elsevier
Cardiovascular events among patients with chronic kidney disease (CKD) are associated
with vascular calcification (VC). Nevertheless, the process of vascular calcification is …
with vascular calcification (VC). Nevertheless, the process of vascular calcification is …
High-Phosphate-stimulated macrophage-derived exosomes promote vascular calcification via let-7b-5p/TGFBR1 axis in chronic kidney disease
Q Li, C Zhang, J Shi, Y Yang, X Xing, Y Wang, X Zhan… - Cells, 2022 - mdpi.com
Although macrophage infiltration has been proven to increase calcified artery media in
chronic kidney disease (CKD) patients, the mechanism by which macrophages are involved …
chronic kidney disease (CKD) patients, the mechanism by which macrophages are involved …
High mobility group box 1 promotes aortic calcification in chronic kidney disease via the Wnt/β-catenin pathway
X Jin, S Rong, W Yuan, L Gu, J Jia, L Wang… - Frontiers in …, 2018 - frontiersin.org
Vascular calcification (VC) is common in chronic kidney disease (CKD), where
cardiovascular mortality remains the leading cause of death. Here, we examined the role of …
cardiovascular mortality remains the leading cause of death. Here, we examined the role of …
Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5
Y Liu, Y Guo, S Bao, H Huang, W Liu, W Guo - Cell Death & Disease, 2022 - nature.com
Vascular calcification (VC) is a significant complication of chronic kidney disease (CKD) and
cellular apoptosis is one of the intricate mechanisms of VC. Bone marrow mesenchymal …
cellular apoptosis is one of the intricate mechanisms of VC. Bone marrow mesenchymal …
[HTML][HTML] Vascular calcification in chronic kidney disease is induced by bone morphogenetic protein-2 via a mechanism involving the Wnt/β-catenin pathway
S Rong, X Zhao, X Jin, Z Zhang, L Chen… - Cellular Physiology and …, 2014 - karger.com
Background: Vascular calcification (VC), in which vascular smooth muscle cells (VSMCs)
undergo a phenotypic transformation into osteoblast-like cells, is one of the emergent risk …
undergo a phenotypic transformation into osteoblast-like cells, is one of the emergent risk …
Exosomal STAT1 derived from high phosphorus‑stimulated vascular endothelial cells induces vascular smooth muscle cell calcification via the Wnt/β‑catenin signaling …
Z Qin, Y Li, J Li, L Jiang, Z Zhang… - International …, 2022 - spandidos-publications.com
Vascular calcification is commonly observed in chronic kidney disease. The mechanism of
how the calcification signal from endothelial cells is transmitted to vascular smooth muscle …
how the calcification signal from endothelial cells is transmitted to vascular smooth muscle …
miR-125b/Ets1 axis regulates transdifferentiation and calcification of vascular smooth muscle cells in a high-phosphate environment
P Wen, H Cao, LI Fang, H Ye, L Jiang, W Su… - Experimental cell …, 2014 - Elsevier
Objectives Vascular calcification is highly prevalent in patients with chronic kidney disease
(CKD) and contributes to increased risk of cardiovascular disease and mortality …
(CKD) and contributes to increased risk of cardiovascular disease and mortality …
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease
W Li, W Feng, X Su, D Luo, Z Li, Y Zhou… - The Journal of …, 2022 - Am Soc Clin Investig
Vascular calcification (VC) is regarded as an important pathological change lacking effective
treatment and associated with high mortality. Sirtuin 6 (SIRT6) is a member of the Sirtuin …
treatment and associated with high mortality. Sirtuin 6 (SIRT6) is a member of the Sirtuin …
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