Antiepileptic drugs and pregnancy outcomes

BJ Wlodarczyk, AM Palacios… - American journal of …, 2012 - Wiley Online Library
The treatment of epilepsy in women of reproductive age remains a clinical challenge. While
most women with epilepsy (WWE) require anticonvulsant drugs for adequate control of their …

Antiepileptic drug exposure and major congenital malformations: the role of pregnancy registries

T Tomson, D Battino, J French, C Harden, L Holmes… - Epilepsy & Behavior, 2007 - Elsevier
The use of antiepileptic drugs (AEDs) in pregnancy is associated with an increased risk of
fetal malformations. Although it is known that AEDs may differ with respect to the type of …

[HTML][HTML] Use of antiepileptic drugs during pregnancy: evolving concepts

PB Pennell - Neurotherapeutics, 2016 - Elsevier
Although prenatal exposure to antiepileptic drugs (AEDs) is known to impart relatively higher
risks of major congenital malformations, prospective studies have provided refined data that …

Antiepileptic drugs during pregnancy: what is known and which AEDs seem to be safest?

PB Pennell - Epilepsia, 2008 - Wiley Online Library
Most infants born to women with epilepsy are healthy, but there are increased risks related
to in utero antiepileptic drug (AED) exposure and seizures. Emerging data from pregnancy …

Pregnancy outcomes in women with epilepsy: a systematic review and meta-analysis of published pregnancy registries and cohorts

K Meador, MW Reynolds, S Crean, K Fahrbach… - Epilepsy research, 2008 - Elsevier
PURPOSE: To conduct a systematic review and meta-analysis to quantify the incidence of
congenital malformations (CMs) and other pregnancy outcomes as a function of in utero anti …

Teratogenic medications and concurrent contraceptive use in women of childbearing ability with epilepsy

J Bhakta, J Bainbridge, L Borgelt - Epilepsy & Behavior, 2015 - Elsevier
Abstract Background Many antiepileptic drugs (AEDs) have the potential to cause
teratogenicity. We evaluated eight antiepileptic drugs (AEDs) classified as Federal Drug …

Management of epilepsy during pregnancy

D Battino, T Tomson - Drugs, 2007 - Springer
Managing epilepsy during pregnancy is to balance the maternal and fetal risks associated
with uncontrolled seizures against the potential teratogenic effects of antiepileptic drugs …

Antiepileptic drugs in women with epilepsy during pregnancy

E Gedzelman, KJ Meador - Therapeutic advances in drug …, 2012 - journals.sagepub.com
Prescribing antiepileptic drugs (AEDs) in pregnancy is a challenge to the clinician. A
multitude of questions arise that must be addressed even prior to conception. In women with …

[HTML][HTML] Antiepileptic drug use during pregnancy: perinatal outcomes

S Kulaga, O Sheehy, AH Zargarzadeh, K Moussally… - Seizure, 2011 - Elsevier
PURPOSE: This study was undertaken to (1) measure the frequency of AED monotherapy or
polytherapy during pregnancy and AED discontinuation prior to pregnancy in a cohort of …

An update on maternal use of antiepileptic medications in pregnancy and neurodevelopment outcomes

EE Gerard, KJ Meador - Journal of pediatric genetics, 2015 - thieme-connect.com
Antiepileptic drugs (AEDs) are prescribed commonly to women of childbearing age. In utero
exposure to some AEDs can have significant cognitive and behavioral consequences for the …