Designing a Multi-Epitope Vaccine against Chlamydia trachomatis by Employing Integrated Core Proteomics, Immuno-Informatics and In Silico Approaches

S Aslam, S Ahmad, F Noor, UA Ashfaq, F Shahid… - Biology, 2021 - mdpi.com
Simple Summary Chlamydia trachomatis is the most common cause of blindness, ectopic
pregnancy, and bacterial sexually transmitted infections. These diseases affect mostly young …

Designing a multi-epitope vaccine against Chlamydia pneumoniae by integrating the core proteomics, subtractive proteomics and reverse vaccinology-based …

F Noor, S Ahmad, M Saleem, H Alshaya… - Computers in Biology …, 2022 - Elsevier
Chlamydia pneumoniae, a pneumonia causing specie belonging to chlamydia bacterium. C.
pneumonia is considered as a leading cause of pneumonia. Apart from that, C. pneumoniae …

Chlamydia trachomatis core genome data mining for promising novel drug targets and chimeric vaccine candidates identification

M Aslam, M Shehroz, F Ali, A Zia, S Pervaiz… - Computers in Biology …, 2021 - Elsevier
Chlamydia trachomatis is involved in most sexually transmitted diseases. The species has
emerged as a major public health threat due to its multidrug-resistant capabilities, and new …

Computational exploration and design of a multi-epitopes vaccine construct against Chlamydia psittaci

AM Alsubaiyel, SI Bukhari - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Chlamydia psittaci is an intracellular pathogen and causes variety of deadly infections in
humans. Antibiotics are effective against C. psittaci however high percentage of resistant …

In silico identification and in vivo analysis of a novel T-cell antigen from Chlamydia, NrdB

CJ Barker, KW Beagley, LM Hafner, P Timms - Vaccine, 2008 - Elsevier
Chlamydial infections are a serious economic burden and health threat to developed and
developing countries. Development of an efficacious vaccine is thought to be the most …

Evaluation of tandem Chlamydia trachomatis MOMP multi-epitopes vaccine in BALB/c mice model

P Jiang, Y Cai, J Chen, X Ye, S Mao, S Zhu, X Xue… - Vaccine, 2017 - Elsevier
Chlamydia trachomatis (Ct), an obligate intracellular parasite, is the leading cause of
bacterial sexually transmitted diseases worldwide. The best solution to control the spread of …

Chlamydia trachomatis: quest for an eye-opening vaccine breakthrough

VP Chavda, A Pandya, E Kypreos… - Expert Review of …, 2022 - Taylor & Francis
Introduction Chlamydia trachomatis, commonly referred to as chlamydia (a bacterium), is a
common sexually transmitted infection, and if attended to early, it can be treatable. However …

[HTML][HTML] In silico prediction of T-and B-cell epitopes in PmpD: First step towards to the design of a Chlamydia trachomatis vaccine

RC Russi, E Bourdin, MI García, CMI Veaute - biomedical journal, 2018 - Elsevier
Background Chlamydia trachomatis is the most common sexually transmitted bacterial
infection globally. Currently, there are no vaccines available despite the efforts made to …

A Multi-Component Prime-Boost Vaccination Regimen with a Consensus MOMP Antigen Enhances Chlamydia trachomatis Clearance

A Badamchi-Zadeh, PF McKay, BT Korber… - Frontiers in …, 2016 - frontiersin.org
Background A vaccine for Chlamydia trachomatis is of urgent medical need. We explored
bioinformatic approaches to generate an immunogen against C. trachomatis that would …

[HTML][HTML] Employing an immunoinformatics approach revealed potent multi-epitope based subunit vaccine for lymphocytic choriomeningitis virus

M Waqas, S Aziz, A Bushra, SA Halim, A Ali… - Journal of Infection and …, 2023 - Elsevier
Background Lymphocytic choriomeningitis virus (LCMV) infects many individuals worldwide
and causes severe infection in the immunosuppressant recipient, spontaneous abortion …