Amyotrophic lateral sclerosis is a pernicious neurodegenerative disorder that is associated
with the progressive degeneration of motor neurons, the disruption of impulse transmission …

Amyotrophic lateral sclerosis (ALS) is a fatal and progressive neurodegenerative disease
affecting upper and lower motor neurons with no cure available. Clinical and animal studies …

Amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease involving loss
of motor neurons (MNs) and muscle atrophy, still has no effective treatment, despite much …

Amyotrophic lateral sclerosis (ALS) is an aggressive and uniformly fatal degenerative
disease of the motor nervous system. In order to understand underlying disease …

The signals that coordinate and control movement in vertebrates are transmitted from
motoneurons (MNs) to their target muscle cells at neuromuscular junctions (NMJs). Human …

Motor neuron loss or degeneration is the typical characteristic of amyotrophic lateral
sclerosis (ALS), which often leads to weakness, paralysis, or even death. The underlying …

Over the years, researchers have leveraged a host of different in vivo models in order to
dissect amyotrophic lateral sclerosis (ALS), a neurodegenerative/neuroinflammatory …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease
affecting upper and lower motor neurons (MNs). To investigate whether Schwann cells could …

Loss of the neuromuscular junction (NMJ) is an early and critical hallmark in all forms of
amyotrophic lateral sclerosis (ALS). Herein, a functional NMJ disease model is developed …

Amyotrophic lateral sclerosis (ALS) is a severe and incurable neurodegenerative disease.
Human motor neurons generated from induced pluripotent stem cells (iPSc) offer new …