The authors were asked by the Editors of ACS Chemical Biology to write an article titled
“Why Nature Chose Selenium” for the occasion of the upcoming bicentennial of the …

There are no two main-group elements that exhibit more similar physical and chemical
properties than sulfur and selenium. Nonetheless, Nature has deemed both essential for life …

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The biological role of selenium is a subject of intense current interest, and the antioxidant
activity of selenoenzymes is now known to be dependent upon redox cycling of selenium …

This review highlights the contributions of Jean Chaudière to the field of selenium
biochemistry. Chaudière was the first to recognize that one of the main reasons that …

Selenium is an essential biological trace element. Adult daily intake of selenium should be
approximately 100 µg per day. This compound has a two-sided effect depending on its …

The unique chemistry of oxygen has been both a resource and threat for life on Earth for at
least the last 2.4 billion years. Reduction of oxygen to water allows extraction of more …

The diverse pharmacological activities of organoselenium compounds are closely correlated
to their ability to scavenge and induce reactive oxygen species (ROS), their intrinsic …

Sulfur and selenium occur in proteins as constituents of the amino acids cysteine,
methionine, selenocysteine, and selenomethionine. Recent research underscores that these …

Selenium has been increasingly recognized as an essential element in biology and
medicine. Its biochemistry resembles that of sulfur, yet differs from it by virtue of both redox …