Ischemia-reperfusion injury is a major cause of acute kidney injury. Recent studies on the
pathophysiology of ischemia-reperfusion-induced acute kidney injury showed that …

As extracellular vesicles that play an active role in intercellular communication by
transferring cellular materials to recipient cells, exosomes offer great potential as a natural …

Exosomes are membrane-enclosed vesicles secreted by cells, containing a variety of
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …

Bone marrow–derived mesenchymal stem cells (BMSCs) have been recently reported to
play a variety of vital roles in organ and tissue damage repair, mainly via potent paracrine …

This study aimed to investigate the underlying mechanism of mesenchymal stem cells
(MSCs) on protection of renal ischemia reperfusion injury (IRI). Exosomes originated from …

Sepsis is a common and life-threatening systemic disorder, often leading to acute injury of
multiple organs. Here, we show that remote ischemic preconditioning (rIPC), elicited by brief …

Background Ischemia–reperfusion injury (IRI)-induced acute kidney injury (AKI) can repair
itself completely. However, most moderate and severe patients undergoing IRI-AKI progress …

Human umbilical cord mesenchymal stem cell-derived exosomes (HucMSC-Ex) are a
promising tool for the repair of acute kidney injury (AKI) caused by cisplatin and …

Endothelial colony forming cell (ECFC)-derived exosomes protect mice against ischemic
kidney injury, via transfer of microRNA-(miR)-486-5p. Mechanisms mediating exosome …

Background Sepsis-associated AKI has been shown to be related to sepsis mortality.
Macrophage activation and endothelial cell damage are involved in the progression of …