Cardiac xenotransplantation from swine has been proposed to “bridge the gap” in supply for
heart failure patients requiring transplantation. Recent preclinical success using genetically …

Survival of pig cardiac xenografts in a non-human primate (NHP) model has improved
significantly over the last 4 years with the introduction of costimulation blockade-based …

Introduction Cardiac xenotransplantation presents significant potential to the field of heart
failure by addressing the high demand for donor organs. The availability of xenograft hearts …

Heart transplantation is the only long-lasting lifesaving option for patients with terminal
cardiac failure. The number of available human organs is however far below the actual …

Background The demand for donated human hearts far exceeds the number available.
Xenotransplantation of genetically modified porcine organs provides an alternative. In 2000 …

Transplantation has been the preferred treatment for severe failure of the heart and other
organs for more than 3 decades. But, for these decades and longer transplantation could be …

Heterotopic cardiac transplantation in the intra-abdominal position in a large animal model
has been essential in the progression of the field of cardiac transplantation. Our group has …

If pig hearts could be transplanted successfully into patients with end-stage cardiac failure,
the critical shortage of hearts from deceased human donors would be overcome. The …

456: Preclinical Orthotopic Cardiac Xenotransplantation - The Journal of Heart and Lung
Transplantation Skip to Main Content Advertisement The Journal of Heart and Lung …

Consistent survival of life-supporting pig heart xenograft recipients beyond 90 days was
recently reported using genetically modified pigs and a clinically applicable drug treatment …