[PDF][PDF] Copper (II) bis (thiosemicarbazone) complexes as potential tracers for evaluation of cerebral and myocardial blood flow with PET

MA Green, DL Klippenstein… - Journal of nuclear …, 1988 - Soc Nuclear Med
Copper(II) Bis(thiosemicarbazone) Complexes as Potential Tracers for Evaluation of Cerebral
and Myocardial Blood Flow with PET Page 1 he zinc-62/copper-62 (62Zn/@Cu) radionucide …

A potential copper radiopharmaceutical for imaging the heart and brain: copper-labeled pyruvaldehyde bis (N4-methylthiosemicarbazone)

MA Green - International Journal of Radiation Applications and …, 1987 - Elsevier
An investigation of the biodistribution of lipophilic copper-64 (half-life= 12.7 h) compounds
has been initiated in order to screen potential tracers that could be used to measure regional …

Evaluation of copper(II)-pyruvaldehyde bis (N-4-methylthiosemicarbazone) for tissue blood flow measurement usina a trapped tracer model

H Young, P Carnochan, J Zweit, J Babich… - European journal of …, 1994 - Springer
Abstract Copper (II)-pyruvaldehyde bis (N-4-methylthiosemicarbazone)(Cu-PTSM) labelled
with 62, 64 Cu is a promising radiotracer for the study of blood flow using positron emission …

[PDF][PDF] Human biodistribution and dosimetry of the PET perfusion agent copper-62-PTSM

TR Wallhaus, J Lacy, J Whang, MA Green… - Journal of Nuclear …, 1998 - Soc Nuclear Med
Copper-62-pyruvaldehyde bis (N4-methyl) thiosemicarbazone (PTSM) has been proposed
as a generator-produced radiopharmaceutical for perfusion imaging using PET. Several …

[PDF][PDF] Copper-62-labeled pyruvaldehyde bis (N4-methylthiosemicarbazonato) copper (II): synthesis and evaluation as a positron emission tomography tracer for …

MA Green, CJ Mathias, MJ Welch… - Journal of Nuclear …, 1990 - Soc Nuclear Med
WestLafayette, Indiana; Division ofRadiation Sciences, Maiinckrodt Institute ofRadiology,
Washington University, St. Louis, Missouri; CardiovascularDivision, Department ofinternal …

[PDF][PDF] Evaluation of a potential generator-produced PET tracer for cerebral perfusion imaging: single-pass cerebral extraction measurements and imaging with …

CJ Mathias, MJ Welch, ME Raichle… - Journal of Nuclear …, 1990 - Soc Nuclear Med
Department ofRadiology, Washington University School ofMedicine, St. Louis, Missouri;
MURR University ofMissouri, Columbia, Missouri; and School ofPharmacy, Purdue …

Mixed bis (thiosemicarbazone) ligands for the preparation of copper radiopharmaceuticals: synthesis and evaluation of tetradentate ligands containing two dissimilar …

JK Lim, CJ Mathias, MA Green - Journal of medicinal chemistry, 1997 - ACS Publications
A series of four “mixed” bis (thiosemicarbazone) keto aldehyde derivatives containing
dissimilar thiosemicarbazone functions were synthesized and evaluated as ligands for …

[PDF][PDF] Technetium-99m bis (aminoethanethiol) complexes with amine sidechains—potential brain perfusion imaging agents for SPECT

SMN Efange, HF Kung, J Billings… - Journal of nuclear …, 1987 - Soc Nuclear Med
T, he search for suitable agents for use as indicators of regional cerebral perfusion has
yielded, in the past few years, the promising agents N, N, N'-trimethyl-N-[2-hydroxy-3-methyl …

[PDF][PDF] Clinical application and quantitative evaluation of generator-produced copper-62-PTSM as a brain perfusion tracer for PET

H Okazawa, Y Yonekura, Y Fujibayashi… - Journal of Nuclear …, 1994 - Soc Nuclear Med
Copper-62-pyruvaldehydebis (N4-methytthiosemicarbazone) copperII (Â@ CU-PTSM)
hasbeenproposedas a generator-pro ducedpositron-emithngtracerforperfusionimaging …

Structure-activity relationships for metal-labeled blood flow tracers: comparison of keto aldehyde bis (thiosemicarbazonato) copper (II) derivatives

EK John, MA Green - Journal of medicinal chemistry, 1990 - ACS Publications
Radiocopper-labeled pyruvaldehyde bis (N4-methylthiosemicarbazonato) copper (II), Cu
[PTSM], is under investigation as a radiopharmaceutical for evaluation of regional blood flow …