Ethnopharmacological relevance Multi-target therapeutics is a promising paradigm for drug
discovery which is expected to produce greater levels of efficacy with fewer adverse effects …

Background. Clinical trials reveal that multiherb prescriptions of herbal medicine often
exhibit pharmacological and therapeutic superiority in comparison to isolated single …

Multi-herb therapy has been widely used in Traditional Chinese medicine and tailored to
meet the specific needs of each individual. However, the potential molecular or systems …

The term systems pharmacology describes a field of study that uses computational and
experimental approaches to broaden the view of drug actions rooted in molecular …

Herbal medicine, a multi-component treatment, has been extensively practiced for treating
various symptoms and diseases. However, its molecular mechanism of action on the human …

Network-based intervention has been a trend of curing systemic diseases, but it relies on
regimen optimization and valid multi-target actions of the drugs. The complex multi …

Introduction In this article, authors report an inclusive discussion about the combinatorial
approach for the treatment of cardiovascular diseases (CVDs) and for counteracting the …

Ethnopharmacological relevance Herbal medicine is a concoction of numerous chemical
ingredients, and it exhibits polypharmacological effects to act on multiple pharmacological …

Current strategies for drug discovery have reached a bottleneck where the paradigm is
generally “one gene, one drug, one disease.” However, using holistic and systemic views …

One of the most difficult problems that hinder the development and application of herbal
medicine is how to illuminate the global effects of herbs on the human body. Currently, the …