An overview of the molecular mechanism of autophagy

Z Yang, DJ Klionsky - Autophagy in infection and immunity, 2009 - Springer
Autophagy is a highly conserved cellular degradation process in which portions of cytosol
and organelles are sequestered into a double-membrane vesicle, an autophagosome, and …

Toward unraveling membrane biogenesis in mammalian autophagy

T Yoshimori, T Noda - Current opinion in cell biology, 2008 - Elsevier
Autophagy is a unique form of membrane trafficking, which delivers macromolecules and
organelles from the cytoplasm to lysosomes for degradation. This fundamental and …

Endocytosis and autophagy: exploitation or cooperation?

SA Tooze, A Abada, Z Elazar - Cold Spring Harbor …, 2014 - cshperspectives.cshlp.org
Autophagy is a lysosome-mediated degradative system that is a highly conserved pathway
present in all eukaryotes. In all cells, double-membrane autophagosomes form and engulf …

[HTML][HTML] Autophagy: machinery and regulation

Z Yin, C Pascual, DJ Klionsky - Microbial cell, 2016 - ncbi.nlm.nih.gov
Macroautophagy/autophagy is an evolutionarily conserved cellular degradation process that
targets cytoplasmic materials including cytosol, macromolecules and unwanted organelles …

Autophagy: molecular machinery for self-eating

T Yorimitsu, DJ Klionsky - Cell Death & Differentiation, 2005 - nature.com
Autophagy is a highly conserved process in eukaryotes in which the cytoplasm, including
excess or aberrant organelles, is sequestered into double-membrane vesicles and delivered …

Emerging regulation and functions of autophagy

P Boya, F Reggiori, P Codogno - Nature cell biology, 2013 - nature.com
Autophagy maintains cell, tissue and organism homeostasis through degradation. Complex
post-translational modulation of the Atg (autophagy-related) proteins adds additional entry …

Dynamics and diversity in autophagy mechanisms: lessons from yeast

H Nakatogawa, K Suzuki, Y Kamada… - Nature reviews Molecular …, 2009 - nature.com
Autophagy is a fundamental function of eukaryotic cells and is well conserved from yeast to
humans. The most remarkable feature of autophagy is the synthesis of double membrane …

Regulation mechanisms and signaling pathways of autophagy

C He, DJ Klionsky - Annual review of genetics, 2009 - annualreviews.org
Autophagy is a process of self-degradation of cellular components in which double-
membrane autophagosomes sequester organelles or portions of cytosol and fuse with …

Autophagy: more than a nonselective pathway

F Reggiori, M Komatsu, K Finley… - International journal of …, 2012 - Wiley Online Library
Autophagy is a catabolic pathway conserved among eukaryotes that allows cells to rapidly
eliminate large unwanted structures such as aberrant protein aggregates, superfluous or …

Biogenesis and cargo selectivity of autophagosomes

H Weidberg, E Shvets, Z Elazar - Annual review of biochemistry, 2011 - annualreviews.org
Autophagy is a major catabolic pathway in eukaryotes, which is required for the
lysosomal/vacuolar degradation of cytoplasmic proteins and organelles. Interest in the …