Lower-extremity artery disease (LEAD) is one of the most frequent modes of clinical
presentation of atherosclerosis worldwide. 1 For the past four decades, the increased risk of …

Caring for patients with lower extremity artery disease: going beyond stents and bypass grafts
Page 1 Caring for patients with lower extremity artery disease: going beyond stents and bypass …

Lower extremity artery disease (LEAD) affects millions of elderly patients and is associated
with elevated cardiovascular morbidity and mortality. Risk factor modification, including the …

: Atherosclerotic cardiovascular disease (ASCVD) is defined as coronary heart disease
(CHD), cerebrovascular disease, or lower extremity arterial disease (LEAD) also named …

Objective/background: Chronic limb threatening ischaemia (CLTI) has a high risk of
amputation and mortality. Increased knowledge on how sex, comorbidities, and medication …

Objective/background Chronic limb threatening ischaemia (CLTI) has a high risk of
amputation and mortality. Increased knowledge on how sex, comorbidities, and medication …

Aims The role and selection of antithrombotic therapy to improve limb outcomes in chronic
lower extremity artery disease (LEAD) is still debated. We conducted a meta-analysis to …

Aims The epidemiology of lower extremity artery disease (LEAD) is evolving. This meta-
analysis of aggregate data aimed to (i) determine the global prevalence of LEAD and by …

The recommendations listed in this guideline are, whenever possible, evidence based. An
initial extensive evidence review, which included literature derived from research involving …

Peripheral artery disease (PAD) is associated with substantial morbidity, including a high
risk of cardiovascular and limb events and death. A growing body of evidence has …