Repair mechanism of Yishen Tongluo formula on mouse sperm DNA fragmentation caused by polystyrene microplastics

C Zhang, Z Wang, S Ma, R Chen, S Wang… - Pharmaceutical …, 2023 - Taylor & Francis
Context Plastics can break down into millions of microplastic (MPs,< 5 mm) particles in the
soil and ocean. These MPs can then affect the function of the reproductive system. There is …

Repair mechanism of Wuwei Fuzheng Yijing formula in di-2-ethylhexyl phthalate-induced sperm DNA fragmentation in mice

C Zhang, S Wang, Z Wang, Q Zhang, R Chen… - Pharmaceutical …, 2022 - Taylor & Francis
Abstract Context Di-2-ethylhexyl phthalate (DEHP), a known persistent organic pollutant,
can increase the sperm DNA fragmentation index (DFI). Objective To investigate the …

Reproductive toxicity of polystyrene microplastics: In vivo experimental study on testicular toxicity in mice

B Hou, F Wang, T Liu, Z Wang - Journal of Hazardous Materials, 2021 - Elsevier
Microplastics (MPS) are widespread in our environment and have a potential impact on the
reproductive development of humans and mammals. In this study, we evaluated the effect of …

Polystyrene microplastics induced male reproductive toxicity in mice

H Jin, T Ma, X Sha, Z Liu, Y Zhou, X Meng… - Journal of Hazardous …, 2021 - Elsevier
Microplastics (MPs) have become hazardous materials, which have aroused widespread
concern about their potential toxicity. However, the effects of MPs on reproductive systems in …

Microplastics cause reproductive toxicity in male mice through inducing apoptosis of spermatogenic cells via p53 signaling

C Lu, Y Liang, Y Cheng, C Peng, Y Sun, K Liu… - Food and Chemical …, 2023 - Elsevier
Background Studies on male reproductive toxicity of microplastics are still scarce and the
precise mechanism is not distinct. Methods C57BL/6 male mice were given oral gavage …

Male reproductive toxicity of polystyrene microplastics: Study on the endoplasmic reticulum stress signaling pathway

S Wen, Y Chen, Y Tang, Y Zhao, S Liu, T You… - Food and Chemical …, 2023 - Elsevier
Microplastics (MPs) have raised health concerns in public for its potential reproductive
toxicity. In this study, we subjected the Kunming mice to 0.01, 0.1 and 1.0 mg/day …

Determination of biological and molecular attributes related to polystyrene microplastic-induced reproductive toxicity and its reversibility in male mice

T Liu, B Hou, Y Zhang, Z Wang - International Journal of Environmental …, 2022 - mdpi.com
Microplastics exist not only in the natural environment, but also in human tissue such as
blood and even placenta. Polystyrene microplastic exposure can cause abnormal sperm …

Co-exposure to polystyrene microplastics and microcystin-LR aggravated male reproductive toxicity in mice

H Liu, H Jin, C Pan, Y Chen, D Li, J Ding… - Food and Chemical …, 2023 - Elsevier
Microplastics (MPs) are plastic pollutants with a diameter of less than 5 mm and microcystins
(MCs) are natural toxins produced by cyanobacteria. In recent years, the pollution of MPs …

Polystyrene microplastics induce blood–testis barrier disruption regulated by the MAPK-Nrf2 signaling pathway in rats

S Li, Q Wang, H Yu, L Yang, Y Sun, N Xu… - … Science and Pollution …, 2021 - Springer
As a persistent pollutant, microplastics (MPs) have been reported to induce sperm quantity
decrease in mice. However, the related mechanism remains obscure. Therefore, this study is …

[HTML][HTML] Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

J Hou, Z Lei, L Cui, Y Hou, L Yang, R An… - Ecotoxicology and …, 2021 - Elsevier
Microplastics (MPs) considered as a new persistent environmental pollutant could enter into
the circulatory system and result in decrease of sperm quantity and quality in mice. However …