Clinical pharmacokinetics of magnesium sulfate in the treatment of children with severe acute asthma

JE Rower, X Liu, T Yu, M Mundorff… - European journal of …, 2017 - Springer
Purpose Intravenous (IV) magnesium sulfate (MgSO 4) is used as adjunct therapy to treat
acute asthma exacerbations. Despite its clinical use, there is a limited understanding of the …

Prospective study of serum and ionized magnesium pharmacokinetics in the treatment of children with severe acute asthma

SM Becker, KM Job, K Lima, TJ Forbes… - European journal of …, 2019 - Springer
Purpose Intravenous (IV) magnesium sulfate (MgSO 4) is clinically useful as adjunct therapy
in treating acute asthma exacerbations. Despite its clinical utility, the disposition of …

Optimizing the use of intravenous magnesium sulfate for acute asthma treatment in children

X Liu, T Yu, JE Rower, SC Campbell… - Pediatric …, 2016 - Wiley Online Library
Background Asthma is the most common pediatric chronic disease and currently affects 7.1
million children in the United States. Many children experience acute asthma exacerbations …

Efficacy of magnesium sulfate treatment in children with acute asthma

A Özdemir, D Doğruel - Medical Principles and Practice, 2020 - karger.com
Objective: Systemic administration of magnesium sulfate (MgSO4) has been proposed as a
treatment for pediatric patients with acute asthma. However, previous trials show mixed …

[HTML][HTML] Magnesium sulfate infusion for acute asthma in the emergency department

JE Irazuzta, N Chiriboga - Jornal de pediatria, 2017 - SciELO Brasil
Objectives: To describe the role of intravenous magnesium sulfate (MgSO4) as therapy for
acute severe asthma in the pediatric emergency department (ED). Source: Publications …

Safety and Effectiveness of Magnesium Sulphate for Severe Acute Asthma Management Among Under-five Children: Systematic Review and Meta-analysis

TA Mega, H Gugsa, H Dejenie, H Hussen… - Journal of Asthma …, 2023 - Taylor & Francis
Background Asthma is the common chronic inflammatory disease affecting children. It is
usually associated with airway hyper-responsiveness. Globally, the prevalence of asthma …

High-dose magnesium sulfate infusion protocol for status asthmaticus: a safety and pharmacokinetics cohort study

TA Egelund, SK Wassil, EM Edwards, S Linden… - Intensive care …, 2013 - Springer
Purpose To assess the safety and pharmacokinetics of high-dose magnesium sulfate (MgSO
4) infusion in pediatric patients with status asthmaticus. Methods A prospective cohort study …

Use of intravenous magnesium sulfate for the treatment of an acute asthma exacerbation in pediatric patients

S Kokotajlo, L Degnan, R Meyers… - The Journal of …, 2014 - meridian.allenpress.com
OBJECTIVES: The standard of care for treatment of an asthma exacerbation includes
oxygen, inhaled short-acting bronchodilators, and systemic corticosteroids; adjunctive …

The role of magnesium sulfate in acute asthma: does route of administration make a difference?

CVE Powell - Current Opinion in Pulmonary Medicine, 2014 - journals.lww.com
MgSO 4 has a role in severe exacerbations of acute asthma and there is no evidence of
benefit outside this clinical situation. Both nebulized and iv treatments are well tolerated and …

[PDF][PDF] A comparative pilot study of the efficacy and safety of nebulized magnesium sulfate and intravenous magnesium sulfate in children with severe acute asthma

T Daengsuwan, S Watanatham - Asian Pacific Journal of Allergy …, 2017 - apjai-journal.org
Introduction: Severe asthma attacks are life-threatening, and require serious medical
attention. Intravenous MgSO4 is an efficient medication, proven to improve outcomes. To …