Decellularized bone matrix is gaining a lot of attention as implantable biomaterials and/or
biological scaffolds for bone tissue repair, and shows good clinical performance. This …

The native extracellular matrix (ECM) provides a matrix to hold tissue/organ, defines the
cellular fate and function, and retains growth factors. Such a matrix is considered as a most …

Autologous bone grafts are commonly used as the gold standard to repair and regenerate
diseased bones. However, they are strongly associated with postoperative complications …

Bone regeneration can be possible through grafts or engineered bone replacement when
bone defects are larger than the critical size. Decellularized bone extracellular matrix (ECM) …

Decellularization is a promising new method to prepare natural matrices for tissue
regeneration. Successful decellularization has been reported using various tissues …

Nowadays, millions of people worldwide are affected by problems of bones and
articulations. These conditions represent about a half of the chronic diseases developed in …

The extracellular matrix (ECM) of mammalian tissues has been isolated, decellularized and
utilized as a scaffold to facilitate the repair and reconstruction of numerous tissues. Recent …

Tissue engineering aims to develop innovative scaffolds for the regeneration of tissues. This
strategy enables hard tissues to heal themselves by the introduction of scaffolds to …

A growing array of synthetic bone regeneration scaffolds has been used or investigated over
the last century. These scaffolds aim to provide a three dimensional substrate for bone cells …

Bone disorders are of significant concern due to increase in the median age of our
population. Traditionally, bone grafts have been used to restore damaged bone. Synthetic …