Endothelial dysfunction and inflammation precedes elevations in blood pressure induced by a high-fat diet

JC Oishi, CA Castro, KA Silva, V Fabricio… - Arquivos brasileiros de …, 2018 - SciELO Brasil
Background: Obesity leads to a chronic inflammatory state, endothelial dysfunction and
hypertension. Objective: To establish the time-course of events regarding inflammatory …

Oxidative stress and inflammatory mediators contribute to endothelial dysfunction in high-fat diet-induced obesity in mice

R Kobayasi, EH Akamine, AP Davel… - Journal of …, 2010 - journals.lww.com
Objective We investigated the effects of high-fat diet-induced obesity on vascular
proinflammatory factors and oxidative stress on endothelium-dependent relaxation of the …

Effects of different degrees of insulin sensitivity on endothelial function in obese patients

R Galvão, FL Plavnik, FF Ribeiro, SA Ajzen… - Arquivos brasileiros de …, 2012 - SciELO Brasil
Background: Obesity derived from intra-abdominal fat deposition tends to increase hormonal
and cytokine production, thus worsening insulin sensitivity and leading to endothelial …

[HTML][HTML] Obesity and coronary artery disease: role of vascular inflammation

F Gomes, DF Telo, HP Souza, JC Nicolau… - Arquivos brasileiros de …, 2010 - SciELO Brasil
A obesidade vem se tornando uma epidemia global. Cerca de 1, 1 bilhões de adultos e
10% das crianças do mundo são atualmente considerados portadores de sobrepeso ou …

[PDF][PDF] Obesity, inflammation and endothelial dysfunction

M Iantorno, U Campia, N Di Daniele… - J Biol Regul Homeost …, 2014 - researchgate.net
169 OBESITY, INFLAMMATION AND ENDOTHELIAL DYSFUNCTION M. IANTORNO1, U.
CAMPIA2, N. DI DANIELE3, S. NISTICÒ4, GB FORLEO3, C. C Page 1 PROOF JOURNAL OF …

Impact of weight loss on adipocytokines, C-reactive protein and insulin sensitivity in hypertensive women with central obesity

RL Borges, FF Ribeiro-Filho, KMB Carvalho… - Arquivos Brasileiros …, 2007 - SciELO Brasil
Objective: To assess the impact of weight reduction on serum adipocytokines, C-reactive
protein (CRP), and insulin sensitivity in hypertensive female patients with central obesity …

Vascular alterations in high-fat diet-obese rats: role of endothelial L-arginine/NO pathway

TB Nascimento, RFF Baptista, PC Pereira… - Arquivos brasileiros de …, 2011 - SciELO Brasil
Background: Mechanisms underlying vascular abnormalities in obesity remain to be
completely clarified. Objective: L-arginine/nitric oxide pathway was evaluated on vascular …

Obesity and endothelial dysfunction

S Taddei, L Ghiadoni, G Salvetti, A Virdis… - Giornale Italiano di …, 2006 - europepmc.org
The endothelium plays a crucial role in modulating vascular function and structure. In
healthy conditions, nitric oxide produced by endothelial cells exerts not only vasodilating …

Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year

P Ziccardi, F Nappo, G Giugliano, K Esposito… - Circulation, 2002 - Am Heart Assoc
Background—Visceral fat is a key regulator site for the process of inflammation, and
atherosclerotic lesions are essentially an inflammatory response. Methods and Results …

The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors

CF Rueda-Clausen, V Lahera, J Calderón… - International journal of …, 2010 - Elsevier
BACKGROUND: Because of the strong association between abdominal obesity (AO) and
other cardiovascular risk factors, it has been difficult to determine which changes in vascular …