TLR signaling: an emerging bridge from innate immunity to atherogenesis
KS Michelsen, TM Doherty, PK Shah… - The Journal of …, 2004 - journals.aai.org
Chronic inflammation and disordered lipid metabolism represent hallmarks of
atherosclerosis. Considerable evidence suggests that innate immune defense mechanisms …
atherosclerosis. Considerable evidence suggests that innate immune defense mechanisms …
Thematic review series: the immune system and atherogenesis. Paying the price for pathogen protection: toll receptors in atherogenesis
P Tobias, LK Curtiss - Journal of lipid research, 2005 - ASBMB
Atherosclerosis is a chronic inflammatory response characterized by the accumulation of
cells of innate and acquired immune systems within the intima of the arterial wall …
cells of innate and acquired immune systems within the intima of the arterial wall …
Innate immune signals in atherosclerosis
AM Lundberg, GK Hansson - Clinical immunology, 2010 - Elsevier
Atherosclerosis is a chronic disease characterised by lipid retention and inflammation in the
arterial intima. Innate immune mechanisms are central to atherogenesis, involving activation …
arterial intima. Innate immune mechanisms are central to atherogenesis, involving activation …
TLR4 signaling: a potential therapeutic target in ischemic coronary artery disease
SJ Jia, PP Niu, JZ Cong, BK Zhang, M Zhao - International …, 2014 - Elsevier
Atherosclerosis has been widely considered as a chronic inflammation process, which
triggers a wide range of cardiovascular diseases such as ischemic coronary artery disease …
triggers a wide range of cardiovascular diseases such as ischemic coronary artery disease …
Toll like receptor 4 in atherosclerosis and plaque destabilization
WK den Dekker, C Cheng, G Pasterkamp, HJ Duckers - Atherosclerosis, 2010 - Elsevier
The immune system plays a pivotal role in initiation and progression of atherosclerosis.
Monocytes and T-lymphocytes are the first cells to enter the damaged endothelium …
Monocytes and T-lymphocytes are the first cells to enter the damaged endothelium …
[HTML][HTML] Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen
C Hayashi, G Papadopoulos, CV Gudino… - The Journal of …, 2012 - journals.aai.org
Clinical and epidemiological studies have implicated chronic infections in the development
of atherosclerosis. It has been proposed that common mechanisms of signaling via TLRs …
of atherosclerosis. It has been proposed that common mechanisms of signaling via TLRs …
Endotoxin, TLR4 signaling and vascular inflammation: potential therapeutic targets in cardiovascular disease
LL Stoll, GM Denning… - Current pharmaceutical …, 2006 - ingentaconnect.com
Cardiovascular disease ranks among the leading causes of morbidity and mortality in adult
populations in the Western world. Significant progress in understanding the etiology of …
populations in the Western world. Significant progress in understanding the etiology of …
TLRs are important inflammatory factors in atherosclerosis and may be a therapeutic target
Y Liu, H Yu, Y Zhang, Y Zhao - Medical Hypotheses, 2008 - Elsevier
Inflammation and immune reactions are implicated in atherogenesis and plaque disruption.
The precise triggers for inflammation in atherosclerosis are not fully understood but may …
The precise triggers for inflammation in atherosclerosis are not fully understood but may …
Immune effector mechanisms implicated in atherosclerosis: from mice to humans
P Libby, AH Lichtman, GK Hansson - Immunity, 2013 - cell.com
According to the traditional view, atherosclerosis results from a passive buildup of
cholesterol in the artery wall. Yet, burgeoning evidence implicates inflammation and immune …
cholesterol in the artery wall. Yet, burgeoning evidence implicates inflammation and immune …
Innate and adaptive immunity in the pathogenesis of atherosclerosis
GK Hansson, P Libby, U Schönbeck… - Circulation research, 2002 - Am Heart Assoc
This review considers critically the evidence for the involvement of mediators of innate and
acquired immunity in various stages of atherosclerosis. Rapidly mobilized arms of innate …
acquired immunity in various stages of atherosclerosis. Rapidly mobilized arms of innate …