[HTML][HTML] Efflux pump mediated antimicrobial resistance by staphylococci in health-related environments: challenges and the quest for inhibition

A Dashtbani-Roozbehani, MH Brown - Antibiotics, 2021 - mdpi.com
The increasing emergence of antimicrobial resistance in staphylococcal bacteria is a major
health threat worldwide due to significant morbidity and mortality resulting from their …

Inhibition of drug efflux pumps in Staphylococcus aureus: current status of potentiating existing antibiotics

BD Schindler, P Jacinto, GW Kaatz - Future microbiology, 2013 - Future Medicine
The emergence of multidrug-resistant Staphylococcus aureus coupled with a declining
output of new antibiotic treatment options from the pharmaceutical industry is a growing …

Multidrug efflux pumps in Staphylococcus aureus and their clinical implications

S Jang - Journal of Microbiology, 2016 - Springer
Antibiotic resistance is rapidly spreading among bacteria such as Staphylococcus aureus,
an opportunistic bacterial pathogen that causes a variety of diseases in humans. For the last …

Synergism between antibiotics and plant extracts or essential oils with efflux pump inhibitory activity in coping with multidrug-resistant staphylococci

M Mikulášová, R Chovanová, Š Vaverková - Phytochemistry Reviews, 2016 - Springer
The alarming growth of the number of antibiotic resistant bacteria and in the same time
limited possibilities to develop new antimicrobial compounds, lead to an urgent need to …

[HTML][HTML] Multidrug efflux pumps in Staphylococcus aureus: an update

SS Costa, M Viveiros, L Amaral… - The open microbiology …, 2013 - ncbi.nlm.nih.gov
The emergence of infections caused by multi-or pan-resistant bacteria in the hospital or in
the community settings is an increasing health concern. Albeit there is no single resistance …

[图书][B] Efflux-mediated antimicrobial resistance in bacteria: mechanisms, regulation and clinical implications

XZ Li, CA Elkins, HI Zgurskaya - 2016 - Springer
Antibiotics are vital to modern medicine. However, bacterial resistance constitutes a growing
threat to effective antimicrobial therapy worldwide. Indeed, antimicrobial resistance …

[HTML][HTML] Resistance to Antimicrobials Mediated by Efflux Pumps in Staphylococcus aureus

SS Costa, E Junqueira, C Palma, M Viveiros… - Antibiotics, 2013 - mdpi.com
Resistance mediated by efflux has been recognized in Staphylococcus aureus in the last
few decades, although its clinical relevance has only been recognized recently. The …

[HTML][HTML] The Major Facilitator Superfamily and Antimicrobial Resistance Efflux Pumps of the ESKAPEE Pathogen Staphylococcus aureus

J Stephen, F Salam, M Lekshmi, SH Kumar, MF Varela - Antibiotics, 2023 - mdpi.com
The ESKAPEE bacterial pathogen Staphylococcus aureus has posed a serious public
health concern for centuries. Throughout its evolutionary course, S. aureus has developed …

Repurposing approved drugs as fluoroquinolone potentiators to overcome efflux pump resistance in Staphylococcus aureus

N Mahey, R Tambat, N Chandal, DK Verma… - Microbiology …, 2021 - Am Soc Microbiol
Staphylococcus aureus is a versatile human commensal bacteria and pathogen that causes
various community and hospital-acquired infections. The S. aureus efflux pump NorA which …

[HTML][HTML] Promising FDA-approved drugs with efflux pump inhibitory activities against clinical isolates of Staphylococcus aureus

SAAM Abdel-Karim, AMA El-Ganiny, MA El-Sayed… - Plos one, 2022 - journals.plos.org
Background and objectives Staphylococcus aureus is an opportunistic pathogen that causes
wide range of nosocomial and community-acquired infections which have spread worldwide …