Current clinical developments in curcumin‐based therapeutics for cancer and chronic diseases

A Kumar, C Harsha, D Parama, S Girisa… - Phytotherapy …, 2021 - Wiley Online Library
The last decade has seen an unprecedented rise in the prevalence of chronic diseases
worldwide. Different mono‐targeted approaches have been devised to treat these multigenic …

Effects of curcumin consumption on human chronic diseases: A narrative review of the most recent clinical data

M Mantzorou, E Pavlidou, G Vasios… - Phytotherapy …, 2018 - Wiley Online Library
Numerous clinical trials have investigated the potential beneficial effects of curcumin
supplementation against several human chronic diseases. Up to now, it has been claimed …

Pharmacological and clinical properties of curcumin

CS Beevers, S Huang - Botanics: Targets and Therapy, 2011 - Taylor & Francis
The polyphenol natural product curcumin has been the subject of numerous studies over the
past decades, which have identified and characterized the compound's pharmacokinetic …

Recent updates on clinical developments of curcumin and its derivatives

P Joshi, A Bisht, A Paliwal, J Dwivedi… - Phytotherapy …, 2023 - Wiley Online Library
Curcumin, a natural polyphenol, derived from Curcuma longa L. is extensively studied by
various researchers across the globe and has established its immense potential in the …

An update on the pharmacological usage of curcumin: has it failed in the drug discovery pipeline?

F Olotu, C Agoni, O Soremekun… - Cell Biochemistry and …, 2020 - Springer
The pharmacological propensities of curcumin have been reported in a plethora of pre-
clinical and clinical studies. However, innate attributes account for extremely low oral …

Curcuma as a functional food in the control of cancer and inflammation

M Schaffer, PM Schaffer, J Zidan… - Current Opinion in …, 2011 - journals.lww.com
Various in-vitro and in-vivo and scarce number of clinical studies on curcumin were
identified. The various effects and properties of curcumin are summarized in this review …

The clinical applications of curcumin: current state and the future

X Fan, C Zhang, D Liu, J Yan… - Current pharmaceutical …, 2013 - ingentaconnect.com
Curcumin is a natural polyphenol product derived from the rhizome of the Curcuma longa. In
vivo and in vitro studies have uncovered many important bioactivities of curcumin, such as …

[HTML][HTML] Pharmacological mechanisms and clinical applications of curcumin: update

M Hao, Y Chu, J Lei, Z Yao, P Wang, Z Chen… - Aging and …, 2023 - ncbi.nlm.nih.gov
Curcumin, a well-known hydrophobic polyphenol extracted from the rhizomes of turmeric
(Curcuma longa L.), has attracted great interest in the last ten years due to its multiple …

Curcumin as a privileged scaffold molecule for various biological targets in drug development

RH Mir, PA Mir, AJ Shah, N Banday, S Sabreen… - Studies in Natural …, 2022 - Elsevier
Abstract Curcumin [1, 7‐bis (4‐hydroxy‐3‐methoxyphenyl)‐1, 6‐heptadiene‐3, 5‐dione] is
pharmacologically active polyphenol isolated from rhizome Curcumin longa L and is a …

Antitumoral activities of curcumin and recent advances to improve its oral bioavailability

MC Nocito, A De Luca, F Prestia, P Avena, D La Padula… - Biomedicines, 2021 - mdpi.com
Curcumin, a main bioactive component of the Curcuma longa L. rhizome, is a phenolic
compound that exerts a wide range of beneficial effects, acting as an antimicrobial …