Glucose is the primary fuel to life on earth. Cellular uptake of glucose is a fundamental
process for metabolism, growth, and homeostasis. Three families of secondary glucose …

The cellular uptake of glucose is an essential physiological process, and movement of
glucose across biological membranes requires specialized transporters. The major facilitator …

Glucose is the major energy source for mammalian cells as well as an important substrate
for protein and lipid synthesis. Mammalian cells take up glucose from extracellular fluid into …

Soluble sugars serve five main purposes in multicellular organisms: as sources of carbon
skeletons, osmolytes, signals, and transient energy storage and as transport molecules …

The human glucose transporters GLUT1 and GLUT3 have a central role in glucose uptake
as canonical members of the Sugar Porter (SP) family. GLUT1 and GLUT3 share a fully …

Glucose is a primary energy source for most cells and an important substrate for many
biochemical reactions. As glucose is a need of each and every cell of the body, so are the …

The glucose transporters (GLUT/SLC2A) are members of the major facilitator superfamily.
Here, we generated a three-dimensional model for Glut1 using a two-step strategy: 1), GlpT …

Glucose enters eucaryotic cells via 2 different types of membrane associated carrier
proteins, the Na+‐coupled glucose transporters (SGLT) and glucose transporter facilitators …

The structure of the human erythrocyte facilitative glucose transporter (GLUT1) has been
intensively investigated using a wide array of chemical and biophysical approaches. Despite …

The liver-type (GLUT2) and brain-type (GLUT3) human facilitative glucose transporters
exhibit distinct kinetics (K m values for deoxyglucose transport of∼ 11 mM and∼ 1.5 mM …