Background As liquid‐based cytology (LBC) specimens harbor high‐quality DNA, genomic
analysis using LBC specimens is beneficial for integrative diagnosis. This study aimed to …

Background Cancer genome profiling of cytology specimens using next‐generation
sequencing (NGS) requires adequate and good‐quality DNA. Genomic examination of …

In addition to conventional cytology, liquid-based cytology (LBC) is also used for
immunocytochemistry and gene analysis. However, an appropriate method to obtain high …

Background Genomic examination of cytology specimens is often performed on cell blocks
or conventional smears rather than on liquid‐based cytology (LBC) specimens. Since LBC …

Molecular diagnosis using DNA and RNA derived from malignant tumors and molecular
biological tools such as the quantitative polymerase‐chain‐reaction (qPCR) is a commonly …

In patients with advanced cancer, it is necessary to detect driver mutations and genetic
arrangements. If a mutation is found, targeted therapy may become an option. However, in …

Liquid-based cytology (LBC) analysis of sputum is a useful diagnostic and prognostic tool for
detecting lung cancer. DNA and RNA derived from lung cancer cells can be used for this …

Background Liquid‐based cytology (LBC) is a widely used method for processing
specimens obtained by endoscopic biopsy. This study evaluated next‐generation …

BACKGROUND Personalized oncology requires molecular analysis of tumor cells. Several
studies have demonstrated that cytological material is suitable for DNA analysis, but to the …

BACKGROUND Next‐generation sequencing (NGS) fails for many small biopsies (BXs)
because of a low overall DNA concentration or tumor percentage. Cytology smears and …