Adverse ventricular remodeling following acute myocardial infarction (MI) may induce
ventricular dilation, fibrosis, and loss of global contractile function, possibly resulting in heart …

Myocardial infarction (MI) results in cardiac myocyte death and the formation of a fibrotic scar
in the left ventricular free wall (LVFW). Following an acute MI, LVFW remodeling takes place …

Ventricular remodeling after myocardial infarction increases the rate of mortality and is
highly associated with the extent of infarct transmurality. It is hypothesized that infarct …

Background Infarct expansion initiates and sustains adverse left ventricular (LV) remodeling
after myocardial infarction (MI) and is influenced by temporal changes in infarct material …

Despite recent advances in the computational modeling of cardiovascular diseases and
therapies, the effect of post-ischemic remodeling has not been thoroughly studied while …

The mechanical properties of healing myocardial infarcts are a critical determinant of pump
function and the transition to heart failure. Recent reports suggest that modifying infarct …

Cardiovascular diseases account for one third of all deaths worldwide, more than 33% of
which are related to ischemic heart disease, including myocardial infarction (MI). This thesis …

Ventricular remodeling may occur following myocardial infarction of the left ventricle (LV)
and such remodeling has been shown to be correlated with increased patient morbidity and …

Cardiac growth and remodeling in the form of chamber dilation and wall thinning are typical
hallmarks of infarct-induced heart failure. Over time, the infarct region stiffens, the remaining …

Acute myocardial infarction (MI) leads to a loss of cardiac function which, following adverse
ventricular remodeling (AVR), can ultimately result in heart failure. Tissue-engineered …