Malic enzyme 1 as a novel anti‐ferroptotic regulator in hepatic ischemia/reperfusion injury

X Fang, J Zhang, Y Li, Y Song, Y Yu, Z Cai… - Advanced …, 2023 - Wiley Online Library
Ferroptosis has been linked to the pathogenesis of hepatic injury induced by
ischemia/reperfusion (I/R). However, the mechanistic basis remains unclear. In this study, by …

Indoleamine 2, 3-dioxygenase 1enhanceshepatocytes ferroptosis in acute immune hepatitis associated with excess nitrative stress

T Zeng, G Deng, W Zhong, Z Gao, S Ma, C Mo… - Free Radical Biology …, 2020 - Elsevier
Ferroptosis is a recently recognized form of regulated cell death that is characterized by lipid
peroxidation. However, the molecular mechanisms of ferroptosis in acute immune hepatitis …

[HTML][HTML] Ferroptosis in hepatic ischemia‑reperfusion injury: Regulatory mechanisms and new methods for therapy

L Luo, G Mo, D Huang - Molecular Medicine Reports, 2021 - spandidos-publications.com
Abstract Ischemia‑reperfusion injury (IRI), also called reoxygenation injury, is the outcome of
inflammatory processes and oxidative damage through the induction of oxidative stress. In …

[HTML][HTML] Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

Y Li, D Feng, Z Wang, Y Zhao, R Sun, D Tian… - Cell Death & …, 2019 - nature.com
Ferroptosis is a recently identified form of regulated cell death defined by the iron-dependent
accumulation of lipid reactive oxygen species. Ferroptosis has been studied in various …

Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis

D Qi, P Chen, H Bao, L Zhang, K Sun, S Song, T Li - Cell cycle, 2023 - Taylor & Francis
Dimethyl fumarate (DMF), a therapeutic agent for relapsing-remitting multiple sclerosis, has
cytoprotective and antioxidant effects. Ferroptosis, a pathological cell death process, is …

The role of ferroptosis in chronic intermittent hypoxia-induced liver injury in rats

LD Chen, RH Wu, YZ Huang, MX Chen, AM Zeng… - Sleep and …, 2020 - Springer
Purpose Obstructive sleep apnea (OSA) has been related to an increased risk of liver injury.
Ferroptosis is a form of programmed cell death implicated in multiple physiological and …

[HTML][HTML] Reclassifying hepatic cell death during liver damage: ferroptosis—a novel form of non-apoptotic cell death?

RU Macías-Rodríguez, ME Inzaugarat… - International journal of …, 2020 - mdpi.com
Ferroptosis has emerged as a new type of cell death in different pathological conditions,
including neurological and kidney diseases and, especially, in different types of cancer. The …

Corilagin attenuates intestinal ischemia/reperfusion injury in mice by inhibiting ferritinophagy-mediated ferroptosis through disrupting NCOA4-ferritin interaction

Y Wang, B Li, G Liu, Q Han, Y Diao, J Liu - Life Sciences, 2023 - Elsevier
Aims Intestinal ischemia reperfusion (II/R) is a common clinical emergency. Ferroptosis is
reported to play a role in II/R injury. Our previous studies revealed that corilagin significantly …

[HTML][HTML] Ferroptosis in liver disease: new insights into disease mechanisms

J Wu, Y Wang, R Jiang, R Xue, X Yin, M Wu… - Cell death …, 2021 - nature.com
Characterized by excessive iron accumulation and lipid peroxidation, ferroptosis is a novel
form of iron-dependent cell death, which is morphologically, genetically, and biochemically …

Nrf2‐Mediated Ferroptosis Inhibition Exerts a Protective Effect on Acute‐on‐Chronic Liver Failure

J Wu, R Xue, M Wu, X Yin, B Xie… - Oxidative Medicine and …, 2022 - Wiley Online Library
Although massive hepatocyte cell death and oxidative stress constitute major events of
acute‐on‐chronic liver failure (ACLF), the relationship of ferroptosis with ACLF has yet to be …