We provide an updated review on the current understanding of breathing and sleep at high
altitude in humans. We conclude that:(1) progressive changes in pH initiated by the …

This review of ventilatory acclimatization to altitude/hypoxia (VAH) emphasizes the widely
differing timescales that VAH is considered to encompass. The review concludes:(1) that …

New arrivals to altitude commonly experience poor-quality sleep. These complaints are
associated with increased fragmentation of sleep by frequent brief arousals, which are in …

Lowlanders commonly report a poor sleep quality during the first few nights after arriving at
high altitude. Polysomnographic studies reveal that reductions in slow wave sleep are the …

To determine whether nocturnal periodic breathing (PB) at altitude is due primarily to
unstable control of ventilation or the inability to maintain stable sleep states, we performed …

The discovery of central sleep apnea (CSA) at high altitude is usually attributed to Angelo
Mosso who published in 1898. It can occur in susceptible individuals at altitude above 2000 …

Acclimatization to long-term hypoxia takes place at high altitude and allows gradual
improvement of the ability to tolerate the hypoxic environment. An important component of …

The ventilatory response to hypoxia is complex. First contact with hypoxia causes an
increase in ventilation within seconds that reaches full intensity within minutes because of …

Intermittent hypoxia is encountered in life more often than sustained hypoxia. The purpose of
this article is to summarize the long-term effects of intermittent hypoxia on control of …

Sleep is known to be impaired at high altitude, and this may be a factor contributing to
reduced work efficiency, general malaise, and the development of acute mountain sickness …