The low-voltage activated T-type calcium channels regulate cellular excitability and
oscillatory behavior of resting membrane potential which trigger many physiological events …

The R-type voltage-gated Ca2+ (Cav) channels Cav2. 3, widely expressed in neuronal and
neuroendocrine cells, represent potential drug targets for pain, seizures, epilepsy, and …

Antihypertensive drugs of the “calcium channel blocker” or “calcium antagonist” class have
been used to establish the physiological role of L-type Ca2+ channels in vascular smooth …

High-voltage-activated R-type CaV2. 3 channel plays pivotal roles in many physiological
activities and is implicated in epilepsy, convulsions, and other neurodevelopmental …

Phosphorylation is a major mechanism regulating the activity of ion channels that remains
poorly understood with respect to T-type calcium channels (Cav3). These channels are low …

Over the years, it has been discussed whether T-type calcium channels Cav3 play a role in
the cardiovascular and renal system. T-type channels have been reported to play an …

Despite their presence in many tissues and their potential implication in various disease
states, low-voltage activated T-type calcium channels (T-channels) have only recently …

L-type calcium channels regulate a diverse array of cellular functions within excitable cells.
Of the four molecularly defined subclasses of L-type Ca channels, two are expressed …

Verapamil is a potent phenylalkylamine antihypertensive believed to exert its therapeutic
effect primarily by blocking high-voltage-activated L-type calcium channels. It was the first …

T-type Ca2+ channels encoded by voltage-gated Ca2+ channel (Cav) 3.1, 3.2, and 3.3
genes play important physiological roles and serve as therapeutic targets for neurological …