Depression and impaired quality of life (QoL) are frequently observed in patients suffering
from HIV-infection. As an enhanced degradation of the serotonin precursor tryptophan is …

Objective Cognitive impairment (CI) and major depressive disorder (MDD) remain prevalent
in treated HIV-1 disease; however, the pathogenesis remains elusive. A possible …

This study examined the role of biological processes in the development of specific
neuropsychiatric complications in HAART-naive adults with HIV/AIDS. Depressive symptoms …

Little is known about the impact of comorbid psychiatric symptoms in health related quality of
life (HRQL) in patients with HIV infection. The aim of this investigation was to describe …

We investigated serum neopterin, tryptophan, and kynurenine concentrations in 23 HIV-1
seropositive patients (Walter Reed Stage 4-6). Ten patients presented with polyneuropathy …

Hematopoietic disturbances are common in patients with HIV-1 infection. Recent studies on
immune activation markers such as neopterin demonstrate that HIV-1 infection is associated …

Neuropsychological impairment and depression are common among individuals with HIV-
infection, resulting in significantly altered everyday functioning. The objective of this study …

Major depression is highly prevalent among HIV‐positive patients (HIV pp). The prevalence
of depression ranges between 18% and 81%, depending on the population studied and the …

This study prospectively evaluated the effect of treatment of major depression on
psychosocial functioning (health-related quality of life (HRQoL)). Previously, we reported on …

Background: Neopterin is a well-established marker of macrophage activation. The
cerebrospinal fluid (CSF) neopterin levels are elevated in most HIV-1-infected individuals …