PPICT: an integrated deep neural network for predicting inter-protein PTM cross-talk
F Zhu, L Deng, Y Dai, G Zhang, F Meng… - Briefings in …, 2023 - academic.oup.com
Post-translational modifications (PTMs) fine-tune various signaling pathways not only by the
modification of a single residue, but also by the interplay of different modifications on residue …
modification of a single residue, but also by the interplay of different modifications on residue …
Systematic characterization and prediction of post-translational modification cross-talk between proteins
Motivation Protein post-translational modifications (PTMs) regulate a wide range of cellular
protein functions. Many PTM sites from the same (intra) or different (inter) proteins often …
protein functions. Many PTM sites from the same (intra) or different (inter) proteins often …
Structure-based prediction of post-translational modification cross-talk within proteins using complementary residue-and residue pair-based features
HF Liu, R Liu - Briefings in Bioinformatics, 2020 - academic.oup.com
Abstract Post-translational modification (PTM)-based regulation can be mediated not only by
the modification of a single residue but also by the interplay of different modifications …
the modification of a single residue but also by the interplay of different modifications …
Ptm-x: Prediction of post-translational modification crosstalk within and across proteins
Y Li, Y Huang, T Li - … Methods for Predicting Post-Translational Modification …, 2022 - Springer
Posttranslational modifications (PTMs), which are processes of adding covalent groups in
protein amino acids after the translation, play an important role in regulating proteins' …
protein amino acids after the translation, play an important role in regulating proteins' …
Systematic characterization and prediction of post-translational modification cross-talk
Post-translational modification (PTM) plays an important role in regulating the functions of
proteins. PTMs of multiple residues on one protein may work together to determine a …
proteins. PTMs of multiple residues on one protein may work together to determine a …
Dual coordination of post translational modifications in human protein networks
Post-translational modifications (PTMs) regulate protein activity, stability and interaction
profiles and are critical for cellular functioning. Further regulation is gained through PTM …
profiles and are critical for cellular functioning. Further regulation is gained through PTM …
dbPTM in 2022: an updated database for exploring regulatory networks and functional associations of protein post-translational modifications
Protein post-translational modifications (PTMs) play an important role in different cellular
processes. In view of the importance of PTMs in cellular functions and the massive data …
processes. In view of the importance of PTMs in cellular functions and the massive data …
Prediction of post-translational modification cross-talk and mutation within proteins via imbalanced learning
L Deng, F Zhu, Y He, F Meng - Expert Systems with Applications, 2023 - Elsevier
Post-translational modification (PTM) is crucial for various cell signaling pathways and
biological processes. However, the interactions between PTMs (PTM cross-talk) or PTMs …
biological processes. However, the interactions between PTMs (PTM cross-talk) or PTMs …
Identification of enriched PTM crosstalk motifs from large-scale experimental data sets
Post-translational modifications (PTMs) play an important role in the regulation of protein
function. Mass spectrometry based proteomics experiments nowadays identify tens of …
function. Mass spectrometry based proteomics experiments nowadays identify tens of …
PTMOracle: a Cytoscape app for covisualizing and coanalyzing post-translational modifications in protein interaction networks
Post-translational modifications of proteins (PTMs) act as key regulators of protein activity
and of protein–protein interactions (PPIs). To date, it has been difficult to comprehensively …
and of protein–protein interactions (PPIs). To date, it has been difficult to comprehensively …