The role of ubiquitination and deubiquitination in cancer metabolism
T Sun, Z Liu, Q Yang - Molecular cancer, 2020 - Springer
Metabolic reprogramming, including enhanced biosynthesis of macromolecules, altered
energy metabolism, and maintenance of redox homeostasis, is considered a hallmark of …
energy metabolism, and maintenance of redox homeostasis, is considered a hallmark of …
Metabolic reprogramming in cancer: Mechanisms and therapeutics
S Nong, X Han, Y Xiang, Y Qian, Y Wei, T Zhang… - MedComm, 2023 - Wiley Online Library
Cancer cells characterized by uncontrolled growth and proliferation require altered
metabolic processes to maintain this characteristic. Metabolic reprogramming is a process …
metabolic processes to maintain this characteristic. Metabolic reprogramming is a process …
Deregulated transcription factors in cancer cell metabolisms and reprogramming
Metabolic reprogramming is an important cancer hallmark that plays a key role in cancer
malignancies and therapy resistance. Cancer cells reprogram the metabolic pathways to …
malignancies and therapy resistance. Cancer cells reprogram the metabolic pathways to …
[HTML][HTML] Oncogenic regulation of tumor metabolic reprogramming
Abstract Development of malignancy is accompanied by a complete metabolic
reprogramming closely related to the acquisition of most of cancer hallmarks. In fact, key …
reprogramming closely related to the acquisition of most of cancer hallmarks. In fact, key …
Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways
MT Snaebjornsson, A Schulze - Experimental & molecular medicine, 2018 - nature.com
The metabolic rewiring that occurs during cell transformation is a hallmark of cancer. It is
diverse in different cancers as it reflects different combinations of oncogenic drivers, tumor …
diverse in different cancers as it reflects different combinations of oncogenic drivers, tumor …
Ubiquitination regulation of aerobic glycolysis in cancer
Y Xie, M Wang, M Xia, Y Guo, X Zu, J Zhong - Life Sciences, 2022 - Elsevier
Aerobic glycolysis, or the Warburg effect, is regarded as a critical part of metabolic
reprogramming and plays a crucial role in the occurrence and development of tumours …
reprogramming and plays a crucial role in the occurrence and development of tumours …
How cancer metabolism is tuned for proliferation and vulnerable to disruption
Cancer metabolism has received a substantial amount of interest over the past decade. The
advances in analytical tools have, along with the rapid progress of cancer genomics …
advances in analytical tools have, along with the rapid progress of cancer genomics …
Metabolic codependencies in the tumor microenvironment
P Dey, AC Kimmelman, RA DePinho - Cancer Discovery, 2021 - AACR
Metabolic reprogramming enables cancer cell growth, proliferation, and survival. This
reprogramming is driven by the combined actions of oncogenic alterations in cancer cells …
reprogramming is driven by the combined actions of oncogenic alterations in cancer cells …
[HTML][HTML] Oncogene-driven metabolic alterations in cancer
HY Min, HY Lee - Biomolecules & therapeutics, 2018 - ncbi.nlm.nih.gov
Cancer is the leading cause of human deaths worldwide. Understanding the biology
underlying the evolution of cancer is important for reducing the economic and social burden …
underlying the evolution of cancer is important for reducing the economic and social burden …
Metabolic reprogramming in colorectal cancer: regulatory networks and therapy
J Zhang, S Zou, L Fang - Cell & Bioscience, 2023 - Springer
With high prevalence and mortality, together with metabolic reprogramming, colorectal
cancer is a leading cause of cancer-related death. Metabolic reprogramming gives tumors …
cancer is a leading cause of cancer-related death. Metabolic reprogramming gives tumors …