Reactive oxygen species (ROS), superoxide anion and hydrogen peroxide, are generated
as byproducts of oxidative phosphorylation in the mitochondria or via cell signaling-induced …

An appropriate balance between self-renewal and differentiation is crucial for stem cell
function during both early development and tissue homeostasis throughout life. Recent …

Significance: Stem cells are characterized by the properties of self-renewal and the ability to
differentiate into multiple cell types, and thus maintain tissue homeostasis. Reactive oxygen …

The majority of research on reactive oxygen species (ROS) has focused on their cellular
toxicities. Stem cells generally have been thought to maintain low levels of ROS as a …

The importance of reactive oxygen species (ROS) has been gradually acknowledged over
the last four decades. Initially perceived as unwanted products of detrimental oxidative …

The cellular formation of reactive oxygen species (ROS) represents an evolutionary ancient
antimicrobial defense system against microorganisms. The NADPH oxidases (NOX), which …

Oxidative stress induced by high levels of reactive oxygen species (ROS) is associated with
the development of different pathological conditions, including cancers and autoimmune …

Reactive oxygen species (ROS), such as the superoxide anion or hydrogen peroxide, have
been established over decades of research as, on the one hand, important and versatile …

Reactive oxygen species (ROS), mostly derived from mitochondrial activity, can damage
various macromolecules and consequently cause cell death. This ROS activity has been …

Reactive oxygen species (ROS), which were originally characterized in terms of their
harmful effects on cells and invading microorganisms, are increasingly implicated in various …