Skeletal muscle or cardiac symptoms are known to appear in a certain proportion of female
patients carrying the dystrophin gene mutation. There is limited high-quality evidence to …

Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive condition caused
primarily by out-of-frame mutations in the dystrophin gene. In males, DMD presents with …

The present study aimed to determine the genetic status of manifesting carriers (MCs) of
Duchenne muscular dystrophy (DMD)/Becker muscular dystrophy (BMD) and asymptomatic …

Duchenne's muscular dystrophy is an X-linked neuromuscular disease that manifests as
muscle atrophy and cardiomyopathy in young boys. However, a considerable percentage of …

Introduction The significance of abnormal cardiac measures in asymptomatic females who
harbor dystrophin gene mutations is controversial. Methods Echo‐measures of ventricular …

Duchenne muscular dystrophy (DMD) is a devastating disease affecting approximately 1 in
every 3,500 male births worldwide. Multiple mutations in the dystrophin gene have been …

Purpose: To review the current understanding of the pathophysiology of dilated
cardiomyopathy (DCM) in patients with Duchenne and Becker muscular dystrophies …

Dystrophin is a large protein serving as local scaffolding repetitively bridging cytoskeleton
and the outside of striated muscle cell. As such dystrophin is a critical brick primarily in …

Mutations in the dystrophin gene cause Duchenne and Becker muscular dystrophies. In
addition to muscle disease, there nearly always is an associated cardiomyopathy in …

A cross-sectional study in a cohort of DNA proven carriers of Duchenne (DMD) and Becker
(BMD) muscular dystrophy was undertaken with the following objectives:(1) to estimate the …