Force-mediating magnetic nanoparticles to engineer neuronal cell function

TJ Gahl, A Kunze - Frontiers in Neuroscience, 2018 - frontiersin.org
Cellular processes like membrane deformation, cell migration, and transport of organelles
are sensitive to mechanical forces. Technically, these cellular processes can be …

Bio‐nano‐magnetic materials for localized mechanochemical stimulation of cell growth and death

D Kilinc, CL Dennis, GU Lee - Advanced materials, 2016 - Wiley Online Library
Magnetic nanoparticles are promising new tools for therapeutic applications, such as
magnetic nanoparticle hyperthermia therapy and targeted drug delivery. Recent in vitro …

Modulating motility of intracellular vesicles in cortical neurons with nanomagnetic forces on-chip

A Kunze, CT Murray, C Godzich, J Lin, K Owsley… - Lab on a Chip, 2017 - pubs.rsc.org
Vesicle transport is a major underlying mechanism of cell communication. Inhibiting vesicle
transport in brain cells results in blockage of neuronal signals, even in intact neuronal …

Magnetic micro-and nanoparticle mediated activation of mechanosensitive ion channels

S Hughes, AJ El Haj, J Dobson - Medical engineering & physics, 2005 - Elsevier
Most cells are known to respond to mechanical cues, which initiate biochemical signalling
pathways and play a role in cell membrane electrodynamics. These cues can be transduced …

Targeted mechanical stimulation via magnetic nanoparticles guides in vitro tissue development

AR Abdel Fattah, N Kolaitis, K Van Daele… - Nature …, 2023 - nature.com
Tissues take shape through a series of morphogenetic movements guided by local cell-
scale mechanical forces. Current in vitro approaches to recapitulate tissue mechanics rely …

Magnetic nanoparticle-based mechanical stimulation for restoration of mechano-sensitive ion channel equilibrium in neural networks

A Tay, D Di Carlo - Nano letters, 2017 - ACS Publications
Techniques offering remote control of neural activity with high spatiotemporal resolution and
specificity are invaluable for deciphering the physiological roles of different classes of …

Remote modulation of neuronal cells in the brain

R Mushi, A Pralle - Nature Materials, 2021 - nature.com
Remote modulation of neuronal cells in the brain | Nature Materials Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Engineering cortical neuron polarity with nanomagnets on a chip

A Kunze, P Tseng, C Godzich, C Murray, A Caputo… - ACS …, 2015 - ACS Publications
Intra-and extracellular signaling play critical roles in cell polarity, ultimately leading to the
development of functional cell–cell connections, tissues, and organs. In the brain …

Induction of calcium influx in cortical neural networks by nanomagnetic forces

A Tay, A Kunze, C Murray, D Di Carlo - Acs Nano, 2016 - ACS Publications
Nanomagnetic force stimulation with ferromagnetic nanoparticles was found to trigger
calcium influx in cortical neural networks without observable cytotoxicity. Stimulated neural …

Parallelized manipulation of adherent living cells by magnetic nanoparticles-mediated forces

M Bongaerts, K Aizel, E Secret, A Jan, T Nahar… - International Journal of …, 2020 - mdpi.com
The remote actuation of cellular processes such as migration or neuronal outgrowth is a
challenge for future therapeutic applications in regenerative medicine. Among the different …