[HTML][HTML] Exposure of trophoblast cells to fine particulate matter air pollution leads to growth inhibition, inflammation and ER stress

M Familari, Å Nääv, L Erlandsson, RU de Iongh… - PloS one, 2019 - journals.plos.org
Ambient air pollution is considered a major environmental health threat to pregnant women.
Our previous work has shown an association between exposure to airborne particulate …

Maternal air pollution exposure during the first trimester of pregnancy and markers of inflammation and endothelial dysfunction

P Mozzoni, S Iodice, N Persico, L Ferrari, S Pinelli… - Environmental …, 2022 - Elsevier
Background Maternal exposure to air pollutants has been associated with pregnancy
complications and adverse birth outcomes. Endothelial dysfunction, an imbalance in …

[HTML][HTML] Cellular mechanisms linking to outdoor and indoor air pollution damage during pregnancy

DI Chiarello, J Ustáriz, R Marín, FS Gallardo… - Frontiers in …, 2023 - frontiersin.org
Pregnancies are a critical window period for environmental influences over the mother and
the offspring. There is a growing body of evidence associating indoor and outdoor air …

[HTML][HTML] Particulate matter, an intrauterine toxin affecting foetal development and beyond

H Chen, BG Oliver, A Pant, A Olivera, P Poronnik… - Antioxidants, 2021 - mdpi.com
Air pollution is the 9th cause of the overall disease burden globally. The solid component in
the polluted air, particulate matters (PMs) with a diameter of 2.5 μm or smaller (PM2. 5) …

Ambient fine particulate matter exposures and human early placental inflammation

C Gong, M Chu, J Yang, X Gong, B Han, L Chen… - Environmental …, 2022 - Elsevier
The effect of fine particulate matter (PM 2.5) on human early maternal–fetal interface is
unknown. We explored the association between maternal exposure to ambient PM 2.5 and …

[HTML][HTML] Urban PM2. 5 induces cellular toxicity, hormone dysregulation, oxidative damage, inflammation, and mitochondrial interference in the HRT8 trophoblast cell …

Å Nääv, L Erlandsson, C Isaxon… - Frontiers in …, 2020 - frontiersin.org
Objective: Epidemiological studies have found air pollution to be a driver of adverse
pregnancy outcomes, including gestational diabetes, low term birth weight and …

[HTML][HTML] Exposure to fine particulate matter in the air alters placental structure and the renin-angiotensin system

SF Soto, JO Melo, GDA Marchesi, KL Lopes… - PLoS …, 2017 - journals.plos.org
Transforming growth factor beta 1 (TGFβ1), the uteroplacental renin-angiotensin system
(RAS) and vascular endothelial growth factor A (VEGF-A) participate in the placentation …

Maternal atmospheric particulate matter exposure and risk of adverse pregnancy outcomes: A meta-analysis of cohort studies

L Ju, L Hua, H Xu, C Li, S Sun, Q Zhang, J Cao… - Environmental …, 2023 - Elsevier
Ambient air particulate exposure not only capable of elevating the risks of adverse
pregnancy outcomes, but also has profound implications for human health, but the results …

Air pollution exposure and markers of placental growth and function: the generation R study

EH van den Hooven, FH Pierik… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Air pollution exposure during pregnancy might affect placental growth and
function, perhaps leading to pregnancy complications. Objective: We prospectively …

Air pollution and pre-eclampsia; associations and potential mechanisms

E Bearblock, CE Aiken, GJ Burton - Placenta, 2021 - Elsevier
Introduction Air pollution has significant negative health impacts, particularly on the
cardiovascular system. The aims of this narrative review were to identify whether there is an …