Complement is a complex protein network of plasma, and an integral part of the innate
immune system. Complement activation results in the rapid clearance of bacteria by immune …

Infectious diseases represent a major health problem. Based on the limited efficacy of
existing drugs and vaccines and the increasing antibiotic resistance new strategies are …

Complement is a central homeotic system of mammals and represents the first defense line
of innate immunity. The human complement system is aimed to maintain homeostasis by …

The human immune system has developed an elaborate network of cascades for dealing
with microbial intruders. Owing to its ability to rapidly recognize and eliminate …

The complement system plays a crucial role in the innate defense against common
pathogens. Activation of complement leads to robust and efficient proteolytic cascades …

Emerging Patterns in Complement-Mediated Pathogen Recognition: Cell Skip to Main Content
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Progress at the beginning of the 21st century transformed the perception of complement
from that of a blood-based antimicrobial system to that of a global regulator of immunity and …

The complement system is an important part of the innate and adaptive immune systems.
Originally characterized as a single serum component contributing to the killing of bacteria …

Complement is traditionally known to be a system of serum proteins that provide protection
against pathogens through direct cell lysis and the mobilization of innate and adaptive …

The complement cascade is an ancient immune‐surveillance system that not only provides
protection from pathogen invasion but has also evolved to participate in physiological …