Ochratoxin A-induced nephrotoxicity: Up-to-date evidence
CS Khoi, JH Chen, TY Lin, CK Chiang… - International journal of …, 2021 - mdpi.com
Ochratoxin A (OTA) is a mycotoxin widely found in various foods and feeds that have a
deleterious effect on humans and animals. It has been shown that OTA causes multiorgan …
deleterious effect on humans and animals. It has been shown that OTA causes multiorgan …
Advances in research of nephrotoxicity and toxic antagonism of ochratoxin A
T Zhao, XL Shen, W Chen, X Liao, J Yang, Y Wang… - Toxin …, 2017 - Taylor & Francis
Ochratoxin A (OTA) is a widespread mycotoxin that naturally takes place in various human
foodstuffs, such as cereals, cereal products, fruits, vegetables, meat, eggs, dairy products …
foodstuffs, such as cereals, cereal products, fruits, vegetables, meat, eggs, dairy products …
Excessive ER-phagy contributes to ochratoxin A-induced apoptosis
H Deng, W Chen, B Zhang, Y Zhang, L Han… - Food and Chemical …, 2023 - Elsevier
The nephrotoxic secondary fungal metabolite ochratoxin A (OTA) is ubiquitously existed in
foodstuffs and feeds. Although our earlier research provided preliminary evidence that …
foodstuffs and feeds. Although our earlier research provided preliminary evidence that …
Transcriptome analysis reveals the AhR, Smad2/3, and HIF-1α pathways as the mechanism of ochratoxin A toxicity in kidney cells
Ochratoxin A (OTA) is a mycotoxin occurring in foods consumed by humans. Recently, there
has been growing global concern regarding OTA toxicity. The main target organ of OTA is …
has been growing global concern regarding OTA toxicity. The main target organ of OTA is …
Renal toxicity through AhR, PXR, and Nrf2 signaling pathway activation of ochratoxin A-induced oxidative stress in kidney cells
Because ochratoxin A (OTA) is widely found in foods, people are susceptible to OTA
exposure. The mechanism leading to renal toxicity induced by OTA remains unclear. The …
exposure. The mechanism leading to renal toxicity induced by OTA remains unclear. The …
[HTML][HTML] Ochratoxin A induces ER stress and apoptosis in mesangial cells via a NADPH oxidase-derived reactive oxygen species-mediated calpain activation pathway
ML Sheu, CC Shen, YS Chen, CK Chiang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Ochratoxin A (OTA) contaminated food increases reactive oxygen species (ROS) production
in glomerulus and causes glomerulopathy. The molecular mechanisms still remain …
in glomerulus and causes glomerulopathy. The molecular mechanisms still remain …
Ochratoxin A-induced cytotoxicity, genotoxicity and reactive oxygen species in kidney cells: An integrative approach of complementary endpoints
Ochratoxin A (OTA) is a well-known nephrotoxic and potential carcinogenic agent but no
consensus about the molecular mechanisms underlying its deleterious effects has been …
consensus about the molecular mechanisms underlying its deleterious effects has been …
Limited link between oxidative stress and ochratoxin A—Induced renal injury in an acute toxicity rat model
Ochratoxin A (OTA) displays nephrotoxicity and hepatotoxicity. However, in the acute toxicity
rat model, there is no evidence on the relationship between OTA and nephrotoxicity and …
rat model, there is no evidence on the relationship between OTA and nephrotoxicity and …
Ochratoxin A induces nephrotoxicity in vitro and in vivo via pyroptosis
H Li, X Mao, K Liu, J Sun, B Li, RM Malyar, D Liu… - Archives of …, 2021 - Springer
Ochratoxin A (OTA), a prevalent nephrotoxic mycotoxin contaminant in food and feedstuff,
has been reported to induce renal injury. To disclose the nephrotoxicity of continuous …
has been reported to induce renal injury. To disclose the nephrotoxicity of continuous …
The multiple biotoxicity integrated study in grass carp (Ctenopharyngodon idella) caused by ochratoxin A: oxidative damage, apoptosis and immunosuppression
P Zhao, X Liu, WD Jiang, P Wu, Y Liu, J Jiang… - Journal of Hazardous …, 2022 - Elsevier
Ochratoxin A (OTA) is a common hazardous food contaminant that seriously endangers
human and animal health. However, limited study is focused on aquatic animal. This …
human and animal health. However, limited study is focused on aquatic animal. This …