[PDF][PDF] In Vitro Investigation of the Antiproliferative and Proapoptotic Effects of Hyperatomarin—A Bicyclic Prenylated Acylphloroglucinol from Hypericum Annulatum …

S Biljali, G Momekov, P Nedialkov… - J. Pharm. Technol …, 2012 - academia.edu
Background: Hyperatomarin is an acylphloroglucinol isolated from H. annulatum Moris
subsp. annulatum, a species endemic for Sardinia and the Balkan Peninsula. Preliminary …

Cytotoxic effects of hyperatomarin, a prenylated phloroglucinol from Hypericum annulatum Moris subsp. annulatum, in a panel of malignant cell lines

G Momekov, D Ferdinandov, D Zheleva-Dimitrova… - Phytomedicine, 2008 - Elsevier
The cytotoxic effects of hyperatomarin–a prenylated phloroglucinol isolated from Hypericum
annulatum Moris subsp. annulatum were assessed in a broad spectrum of tumor cell lines …

Three new prenyloxy chromanones from aerial parts of Hypericum aucheri

PT Nedialkov, Y Ilieva, D Zheleva-Dimitrova… - Fitoterapia, 2019 - Elsevier
Three new prenyloxy chromanone derivatives, aucherine AC (6, 7 and 9) as well as six
known prenylated phloroglucinols (1–5 and 8) were isolated from the aerial parts of …

Cytotoxic prenylated acylphloroglucinols from Hypericum annulatum

PT Nedialkov, Y Ilieva, G Momekov… - Fitoterapia, 2018 - Elsevier
A phytochemical investigation of the aerial parts of Hypericum annulatum Moris led to the
isolation of five new prenylated acylphloroglucinol derivatives hyperannulatins AE (1–3, 5 …

Bioactive acylphloroglucinols from Hypericum densiflorum

GE Henry, MS Campbell, AA Zelinsky… - Phytotherapy …, 2009 - Wiley Online Library
Three acylphloroglucinol derivatives have been isolated from the hexane and acetone
extracts of the aerial parts of Hypericum densiflorum Pursch. The compounds were …

Prenylated acylphloroglucinols from Hypericum annulatum

P Nedialkov, Y Ilieva, G Momekov - Planta Medica, 2015 - thieme-connect.com
The genus Hypericum L.(Hypericaceae) includes more than 480 species that are found in
every continent of the world, except Antarctica [1]. Hypericum annulatum Moris is a perennial …

Antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivatives from Hypericum amblycalyx

K Winkelmann, M San, Z Kypriotakis… - … für Naturforschung C, 2003 - degruyter.com
Two new bicyclic acylphloroglucinol derivatives, hypercalyxone A (1-[5, 7-dihydroxy-2-
methyl-3-(3-methyl-but-2-enyl)-2-(4-methyl-pent-3-enyl)-chroman-8-yl]-2-methyl-propan-1 …

Rare biscoumarin derivatives and flavonoids from Hypericum riparium

SAF Tanemossu, K Franke, N Arnold, J Schmidt… - Phytochemistry, 2014 - Elsevier
Hypericum riparium A. Chev. is a Cameroonian medicinal plant belonging to the family
Guttiferae. Chemical investigation of the methanol extract of the stem bark of H. riparium led …

Antiproliferative activity of the dimeric phloroglucinol and benzophenone derivatives of Hypericum spp. native to southern Brazil

AV Pinhatti, FMC de Barros, CB de Farias… - Anti-Cancer …, 2013 - journals.lww.com
A large number of plants are known to possess strong antitumor properties. Previous studies
have verified the antiproliferative activity of the extracts and fractions from six species of …

Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically …

K Hostanska, J Reichling, S Bommer, M Weber… - European Journal of …, 2003 - Elsevier
Hyperforin (HP) is an abundant component of St John's wort with antibiotic and
antidepressive activity. We report here the ability of HP and that of polyphenolic procyanidin …